Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ALPL | P05186 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6703999 | 0.93 | MAPT (0.39) | MAPTALDH1A1RXFP1HSD17B10LMNA | |
| SCHEMBL6705261 | 0.89 | MAPT (0.30) | MAPTRXFP1HSD17B10GAA | |
| SCHEMBL6703731 | 0.89 | MAPT (0.34) | MAPTALDH1A1RXFP1HSD17B10LMNA | |
| SCHEMBL6703661 | 0.83 | MEN1 (0.32) | MAPTRXFP1LMNA | |
| SCHEMBL6704672 | 0.83 | TSHR (0.30) | — | |
| SCHEMBL6702291 | 0.83 | — | — | |
| SCHEMBL6702904 | 0.82 | MAPT (0.33) | MAPTALDH1A1HSD17B10LMNAGAA | |
| SCHEMBL6702447 | 0.79 | MAPT (0.38) | MAPTALDH1A1RXFP1HSD17B10LMNA | |
| SCHEMBL7087093 | 0.78 | MAPT (0.39) | MAPTALDH1A1RXFP1HSD17B10LMNA | |
| SCHEMBL6704674 | 0.77 | MAPT (0.31) | MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198793-A1 | Chemical process and new intermediates | SANOFI-SYNTHELABO (FR) | 2004-10-07 | — | — | US | disclosed |
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |