Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6702904 | 0.94 | MAPT (0.33) | MAPTHSD17B10GAA | |
| SCHEMBL6703731 | 0.90 | MAPT (0.34) | MAPTHSD17B10HTTRXFP1GAA | |
| SCHEMBL6704672 | 0.89 | TSHR (0.30) | — | |
| SCHEMBL6704682 | 0.89 | MAPT (0.36) | MAPTHSD17B10RXFP1GAA | |
| SCHEMBL6702291 | 0.86 | — | — | |
| SCHEMBL6703661 | 0.84 | MEN1 (0.32) | MAPTHTTRXFP1 | |
| SCHEMBL6702447 | 0.83 | MAPT (0.38) | MAPTHSD17B10RXFP1GAA | |
| SCHEMBL6703999 | 0.83 | MAPT (0.39) | MAPTHSD17B10RXFP1GAA | |
| SCHEMBL6704674 | 0.83 | MAPT (0.31) | MAPTGAA | |
| SCHEMBL6700564 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198793-A1 | Chemical process and new intermediates | SANOFI-SYNTHELABO (FR) | 2004-10-07 | — | — | US | disclosed |
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |