SCHEMBL6704713

SCHEMBL6704713

C=CC[C@H](Cl)CNC(N)=O

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.34
GRIK1 P39086 2/20 0.32
GRIK2 Q13002 2/20 0.32
ALDH1A1 P00352 2/20 0.32
TSHR P16473 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CPA1 P15085 1/20 0.32
MAPT P10636 1/20 0.31
CACNA1B Q00975 1/20 0.31
APBA1 Q02410 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29215688 0.73 BCAT2 (0.33) BCAT2GRIK1GRIK2ALDH1A1TSHR
SCHEMBL8040715 0.71
SCHEMBL5132328 0.70 BCAT2 (0.38) BCAT2ALDH1A1TSHRMAPTCACNA1B
SCHEMBL15467869 0.67
SCHEMBL11391082 0.67 BCAT2 (0.39) BCAT2ALDH1A1TSHR
SCHEMBL4299230 0.67 BCAT2 (0.33) BCAT2
SCHEMBL10770048 0.67
SCHEMBL29510 0.66
SCHEMBL21516153 0.66
SCHEMBL28118435 0.65 BCAT2 (0.39) BCAT2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004106292-A1 HALOETHYL UREA COMPOUNDS AND THEIR USE TO ATTENUATE, INHIBIT OR PREVENT NON-CANCEROUS PATHOGENIC CELLULAR PROLIFERATION AND DISEASES ASSOCIATED THEREWITH IMOTEP INC. (CA) 2004-12-09 WO disclosed