Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 20/20 | 0.63 |
| ▸ | KIT | P10721 | 3/20 | 0.54 |
| ▸ | FLT3 | P36888 | 3/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6704570 | 0.90 | PDGFRB (0.79) | PDGFRBKITFLT3PDGFRA | |
| SCHEMBL6704362 | 0.90 | PDGFRB (0.79) | PDGFRBKITFLT3PDGFRA | |
| SCHEMBL6703372 | 0.88 | PDGFRB (0.80) | PDGFRBKITFLT3PDGFRA | |
| SCHEMBL906248 | 0.85 | PDGFRB (0.75) | PDGFRBKITFLT3PDGFRA | |
| SCHEMBL6700735 | 0.79 | PDGFRB (0.53) | PDGFRBKITFLT3 | |
| SCHEMBL1132325 | 0.78 | PDGFRB (0.64) | PDGFRBKITPDGFRA | |
| SCHEMBL3366895 | 0.78 | PDGFRB (0.73) | PDGFRBKITFLT3PDGFRA | |
| SCHEMBL6950156 | 0.77 | KDM1A (0.57) | PDGFRBKITPDGFRA | |
| SCHEMBL906239 | 0.77 | PDGFRB (1.00) | PDGFRBKITFLT3PDGFRA | |
| SCHEMBL6703374 | 0.76 | PDGFRB (1.00) | PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040259881-A1 | Nitrogenous heterocyclic compounds | KYOWA HAKKO KOGYO CO, LTD. (JP) | 2004-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259881-A1 | Nitrogenous heterocyclic compounds | WNK2, CDK5, PDGFRA | PDGFRB 5/4885KIT 657/4885FLT3 438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.