SCHEMBL6705334

SCHEMBL6705334

C=CCOC(=O)c1ccc(S(N)(=O)=O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA2 P00918 10/20 0.59
CA1 P00915 9/20 0.59
CA9 Q16790 9/20 0.59
CA12 O43570 8/20 0.59
CA14 Q9ULX7 5/20 0.59
CA7 P43166 2/20 0.57
CA4 P22748 2/20 0.56
SNCA P37840 1/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
CYP3A4 P08684 1/20 0.49
CA3 P07451 1/20 0.49
CA6 P23280 1/20 0.49
CYP2C19 P33261 1/20 0.49
CA5A P35218 1/20 0.49
CA5B Q9Y2D0 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11804202 0.87 SNCA (0.55) CA2CA1CA9CA12CA14
SCHEMBL175786 0.84 SNCA (0.67) CA2CA1CA9CA12CA14
SCHEMBL250839 0.80 CYP3A4 (0.59) SNCACYP3A4CYP2C19
SCHEMBL461801 0.79 SNCA (0.61) SNCAMEN1KMT2ACYP3A4
SCHEMBL17386391 0.79 SNCA (0.61) CA2CA1CA9CA12CA14
SCHEMBL6502299 0.78 KMT2A (0.78) CA2CA1CA9CA12CA14
SCHEMBL7460913 0.78 SNCA (0.47) CA2CA1CA9CA12CA14
SCHEMBL175787 0.78 SNCA (0.59) SNCAMEN1KMT2ACYP3A4
SCHEMBL5675836 0.78 SNCA (0.59) CA2CA1CA9CA12CA14
SCHEMBL31182 0.78 SNCA (0.59) CA2CA1CA9CA12CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4662319-A2 PERSONALIZED CRISPR PROFILING FOR CANCER Integrate Bioscience LLC (US) 2025-12-17 EP disclosed
WO-2024168301-A2 PERSONALIZED CRISPR PROFILING FOR CANCER FUNCTION ONCOLOGY, INC. (US) 2024-08-15 WO disclosed
US-6723749-B2 TREATING BACTERIAL INFECTIONS SMITHKLINE BEECHAM CORPORATION 2004-04-20 US disclosed
US-20040058988-A1 FATTY ACID SYNTHASE INHIBITORS GLAXOSMITHKLINE LLC 2004-03-25 US disclosed
EP-1322331-A2 FATTY ACID SYNTHASE INHIBITORS SmithKline Beecham Corporation (US) 2003-07-02 EP disclosed
EP-1318803-A1 FATTY ACID SYNTHASE INHIBITORS SmithKline Beecham Corporation (US) 2003-06-18 EP disclosed
WO-2002009651-A2 FATTY ACID SYNTHASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2002-02-07 WO disclosed
WO-2002009688-A1 FATTY ACID SYNTHASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2002-02-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040058988-A1 FATTY ACID SYNTHASE INHIBITORS FASN, FADS1, FADS2 CA2 2194/4885CA1 2910/4885CA9 2071/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.