SCHEMBL6705877

SCHEMBL6705877

CCCCC/C=C/C/C=C/C/C=C/C/C=C/CCCC(=O)Nc1ccc(O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 8/20 1.00
CNR2 P34972 6/20 1.00
PSMB11 A5LHX3 3/20 1.00
PSMA7 O14818 3/20 1.00
PSMB1 P20618 3/20 1.00
PSMA1 P25786 3/20 1.00
PSMA2 P25787 3/20 1.00
PSMA3 P25788 3/20 1.00
PSMA4 P25789 3/20 1.00
PSMB8 P28062 3/20 1.00
PSMB9 P28065 3/20 1.00
PSMA5 P28066 3/20 1.00
PSMB4 P28070 3/20 1.00
PSMB6 P28072 3/20 1.00
PSMB5 P28074 3/20 1.00
PSMB10 P40306 3/20 1.00
PSMB3 P49720 3/20 1.00
PSMB2 P49721 3/20 1.00
PSMA6 P60900 3/20 1.00
PSMA8 Q8TAA3 3/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL157919 1.00 CNR1 (1.00) CNR1CNR2PSMB11PSMA7PSMB1
SCHEMBL1395702 1.00 CNR1 (1.00) CNR1CNR2PSMB11PSMA7PSMB1
SCHEMBL8390708 0.96 PSMB11 (0.94) CNR1CNR2PSMB11PSMA7PSMB1
SCHEMBL8389682 0.93 PSMB11 (1.00) CNR1CNR2PSMB11PSMA7PSMB1
SCHEMBL8589573 0.93 PSMB11 (1.00) CNR1CNR2PSMB11PSMA7PSMB1
SCHEMBL8589576 0.93 PSMB11 (1.00) CNR1CNR2PSMB11PSMA7PSMB1
SCHEMBL18240151 0.87 SOAT2 (0.86) CNR1CNR2PSMB11PSMA7PSMB1
SCHEMBL18240149 0.87 SOAT2 (0.86) CNR1CNR2PSMB11PSMA7PSMB1
SCHEMBL23021636 0.86 CNR1 (0.76) CNR1CNR2PSMB11PSMA7PSMB1
SCHEMBL8622052 0.85 PSMB11 (0.85) CNR1CNR2PSMB11PSMA7PSMB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040204486-A1 Anandamide and structurally related lipids as vanilloid receptor modulators HOGESTATT EDWARD (SE) 2004-10-14 US disclosed
US-20020019444-A1 Anandamide and structurally related lipids as vanilloid receptor modulators HOGESTATT EDWARD (SE) 2002-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019444-A1 Anandamide and structurally related lipids as vanilloid receptor modulators TRPV1, CNR2, CNR1 CNR1 3/4885CNR2 2/4885PSMB11 2928/4885
US-20040204486-A1 Anandamide and structurally related lipids as vanilloid receptor modulators TRPV1, CNR2, CNR1 CNR1 3/4885CNR2 2/4885PSMB11 2928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.