Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 3/20 | 0.52 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6705890 | 0.89 | NAMPT (0.60) | MCHR1CYP2D6CHRM1HTR2AALDH1A1 | |
| SCHEMBL6705916 | 0.81 | CHRM4 (0.69) | MCHR1CHRM1KMT2AALDH1A1KDM4E | |
| SCHEMBL6704792 | 0.80 | MEN1 (0.61) | KMT2AHRH3MEN1SMN1; SMN2 | |
| SCHEMBL6704754 | 0.79 | MCHR1 (0.52) | MCHR1CYP2D6CHRM1HTR2AKMT2A | |
| SCHEMBL6705906 | 0.79 | MCHR1 (0.52) | MCHR1CYP2D6CHRM1HTR2AKMT2A | |
| SCHEMBL6704534 | 0.78 | L3MBTL3 (0.59) | MCHR1CYP2D6CHRM1HTR2ACYP3A4 | |
| SCHEMBL6704726 | 0.78 | MAPT (0.56) | MCHR1CYP2D6CHRM1HTR2AHRH3 | |
| SCHEMBL311932 | 0.78 | GAA (0.67) | KMT2AALDH1A1TDP1HRH3MEN1 | |
| SCHEMBL6706014 | 0.78 | CHRM4 (0.54) | MCHR1CYP2D6CHRM1HTR2AALDH1A1 | |
| SCHEMBL6705783 | 0.78 | CHRM4 (0.70) | MCHR1CYP2D6CHRM1HTR2AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040242572-A1 | New carboxamide compounds having melanin concentrating hormone antagonistic activity, pharmaceutical preparations comprising these compounds and process for their manufacture | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242572-A1 | New carboxamide compounds having melanin concentrating hormone antagonistic activity, pharmaceutical preparations comprising these compounds and process for their manufacture | MCHR2, MCHR1, NPY1R | PRMT5 188/4885WDR77 1703/4885HDAC1 2047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.