Methane

Methane

SCHEMBL6706124

C.C.O=C(O)C1CCC2CCCC=C2C1C(=O)O

nearest known ligand 0.36

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Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.34
AKR1C1 Q04828 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL6706127 0.74 HCAR2 (0.31)
SCHEMBL28036571 0.72 HCAR2 (0.32)
SCHEMBL5969467 0.68 AKR1C3 (0.32) AKR1C3AKR1C1
SCHEMBL3099636 0.67 AKR1C3 (0.34) AKR1C3AKR1C1
SCHEMBL14879909 0.66 ESR2 (0.31)
SCHEMBL22607746 0.65 KDM4E (0.37)
SCHEMBL22607747 0.65 KDM4E (0.37)
SCHEMBL1123913 0.63 KDM1A (0.31)
SCHEMBL7185201 0.63 GLS (0.30)
SCHEMBL18095592 0.63 KDM4E (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2004530573-A 2004-10-07 JP claimed
US-20040015261-A1 Shape memory polymer or alloy ophthalmic lens mold and methods of forming ophthalmic products JOHNSON & JOHNSON VISION CARE, INC. 2004-01-22 US claimed
EP-1373340-A1 SHAPE MEMORY POLYMER OR ALLOY OPHTHALMIC LENS MOLD AND METHODS OF FORMING OPHTHALMIC PRODUCTS Johnson & Johnson Vision Care, Inc. (US) 2004-01-02 EP claimed
WO-2002059169-A9 SHAPE MEMORY POLYMER OR ALLOY OPHTHALMIC LENS MOLD AND METHODS OF FORMING OPHTHALMIC PRODUCTS JOHNSON & JOHNSON VISION CARE (US) 2003-01-09 WO claimed
WO-2002059169-A1 SHAPE MEMORY POLYMER OR ALLOY OPHTHALMIC LENS MOLD AND METHODS OF FORMING OPHTHALMIC PRODUCTS JOHNSON & JOHNSON VISION CARE , INC. (US) 2002-08-01 WO claimed