Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALML3 | P27482 | 6/20 | 0.40 |
| ▸ | MAOA | P21397 | 8/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6706405 | 1.00 | CALML3 (0.40) | CALML3MAOAMAOB | |
| SCHEMBL6631955 | 0.89 | MAOA (0.54) | CALML3MAOAMAOB | |
| SCHEMBL6706126 | 0.89 | MAOA (0.54) | CALML3MAOAMAOB | |
| SCHEMBL6636444 | 0.86 | CALML3 (0.45) | CALML3MAOAMAOB | |
| SCHEMBL6636442 | 0.86 | CALML3 (0.45) | CALML3MAOAMAOB | |
| SCHEMBL6706122 | 0.85 | MAOA (0.35) | CALML3MAOAMAOB | |
| SCHEMBL6631952 | 0.85 | MAOA (0.35) | CALML3MAOAMAOB | |
| SCHEMBL6635519 | 0.81 | CALML3 (0.48) | CALML3MAOAMAOB | |
| SCHEMBL6706437 | 0.81 | CALML3 (0.48) | CALML3MAOAMAOB | |
| SCHEMBL6638909 | 0.80 | CALML3 (0.48) | CALML3MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6828317-B2 | Bactericides; gramnegative, grampositive bacteria | PHARMACIA & UPJOHN COMPANY | 2004-12-07 | — | — | US | disclosed |
| US-20040014746-A1 | Antimicrobial thiadiazinone derivatives and their application for treatment of bacterial infections | LEUHR GARY W (US) | 2004-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014746-A1 | Antimicrobial thiadiazinone derivatives and their application for treatment of bacterial infections | TBCD, THPO, NISCH | CALML3 4231/4885MAOA 2120/4885MAOB 1467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.