Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 8/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GYS1 | P13807 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10754807 | 0.83 | ACE (0.39) | ACEP2RX7KMT2AMEN1POLB | |
| SCHEMBL7826338 | 0.83 | ACE (0.39) | ACEP2RX7KMT2AMEN1POLB | |
| SCHEMBL12923195 | 0.83 | P2RX7 (0.36) | ACEP2RX7CHRM2CHRM4CHRM5 | |
| SCHEMBL16515479 | 0.81 | KMT2A (0.41) | P2RX7KMT2AMEN1ALDH1A1 | |
| SCHEMBL983163 | 0.81 | KMT2A (0.41) | P2RX7KMT2AMEN1ALDH1A1 | |
| SCHEMBL28627005 | 0.80 | ACE (0.39) | ACEP2RX7CHRM2CHRM4CHRM5 | |
| SCHEMBL16521964 | 0.80 | P2RX7 (0.39) | P2RX7CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL1914212 | 0.77 | P2RX7 (0.51) | ACEP2RX7KMT2A | |
| SCHEMBL1587390 | 0.77 | P2RX7 (0.51) | ACEP2RX7KMT2A | |
| SCHEMBL6694973 | 0.77 | ACE (0.44) | ACEP2RX7KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004137178-A | PYRROLIDINONE DERIVATIVE AND METHOD FOR PRODUCING THE SAME | MITSUBISHI RAYON CO LTD | 2004-05-13 | — | — | JP | disclosed |