SCHEMBL6707007

SCHEMBL6707007

CCCCCC=CCC=CCC=CCC=CCCCCNCCc1ccc(O)c(OC)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 6/20 0.62
MAPT P10636 3/20 0.62
HPGD P15428 3/20 0.62
ALDH1A1 P00352 2/20 0.62
HTR1A P08908 3/20 0.61
CYP1A2 P05177 2/20 0.61
CYP3A4 P08684 2/20 0.61
CYP2D6 P10635 2/20 0.61
LTA4H P09960 2/20 0.61
CYP2E1 P05181 1/20 0.61
ALOX5 P09917 1/20 0.61
CYP2C8 P10632 1/20 0.61
CYP2A6 P11509 1/20 0.61
CYP2C9 P11712 1/20 0.61
CYP2B6 P20813 1/20 0.61
CYP2C19 P33261 1/20 0.61
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
TP53 P04637 1/20 0.57
MTOR P42345 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6707005 1.00 TRPV1 (0.62) TRPV1MAPTHPGDALDH1A1HTR1A
SCHEMBL28531966 0.96 HTR1A (0.65) TRPV1MAPTHPGDALDH1A1HTR1A
SCHEMBL3957501 0.90 CYP1A2 (0.60) HTR1ACYP1A2CYP3A4CYP2C8CYP2C9
SCHEMBL29207410 0.89 TRPV1 (0.69) TRPV1MAPTHPGDALDH1A1CYP1A2
SCHEMBL6705873 0.87 TRPV1 (0.54) TRPV1MAPTHPGDALDH1A1HTR1A
SCHEMBL6705870 0.87 TRPV1 (0.54) TRPV1MAPTHPGDALDH1A1HTR1A
SCHEMBL29517055 0.87 MAPT (0.69) TRPV1MAPTHPGDALDH1A1CYP1A2
SCHEMBL94205 0.87 MAPT (0.69) TRPV1MAPTHPGDALDH1A1CYP1A2
SCHEMBL94204 0.87 MAPT (0.69) TRPV1MAPTHPGDALDH1A1CYP1A2
SCHEMBL5537900 0.86 TRPV1 (0.69) TRPV1MAPTHPGDALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040204486-A1 Anandamide and structurally related lipids as vanilloid receptor modulators HOGESTATT EDWARD (SE) 2004-10-14 US disclosed
US-20020019444-A1 Anandamide and structurally related lipids as vanilloid receptor modulators HOGESTATT EDWARD (SE) 2002-02-14 US disclosed
WO-2001085158-A2 ANANDAMIDE AND STRUCTURALLY RELATED LIPIDS AS VANILLOID RECEPTOR MODULATORS FORSKARPATENT I SYD AB (SE) 2001-11-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019444-A1 Anandamide and structurally related lipids as vanilloid receptor modulators TRPV1, CNR2, CNR1 TRPV1 1/4885MAPT 4147/4885HPGD 1173/4885
US-20040204486-A1 Anandamide and structurally related lipids as vanilloid receptor modulators TRPV1, CNR2, CNR1 TRPV1 1/4885MAPT 4147/4885HPGD 1173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.