Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.41 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5929882 | 0.94 | CYP1A2 (0.44) | L3MBTL1NPC1RAB9AGAAHDAC3 | |
| SCHEMBL3351804 | 0.91 | L3MBTL1 (0.60) | L3MBTL1POLBNPC1RAB9AGAA | |
| SCHEMBL9660491 | 0.79 | L3MBTL1 (0.45) | L3MBTL1POLBNPC1RAB9AGAA | |
| SCHEMBL6570711 | 0.77 | HDAC3 (0.44) | L3MBTL1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL31560011 | 0.77 | CYP1A2 (0.44) | NPC1RAB9AGAAHDAC3HDAC4 | |
| SCHEMBL8649160 | 0.77 | GAA (0.65) | L3MBTL1POLBNPC1RAB9AGAA | |
| SCHEMBL9660925 | 0.77 | GAA (0.65) | L3MBTL1POLBNPC1RAB9AGAA | |
| SCHEMBL28305561 | 0.77 | L3MBTL1 (0.57) | L3MBTL1POLBNPC1RAB9AGAA | |
| SCHEMBL31560000 | 0.76 | CA12 (0.46) | NPC1RAB9AGAAHDAC3HDAC4 | |
| SCHEMBL31560021 | 0.76 | CYP1A2 (0.43) | NPC1RAB9AGAAHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392315-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002100410-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-12-19 | — | — | WO | disclosed |