Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 7/20 | 0.34 |
| ▸ | RAB9A | P51151 | 6/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2065802 | 0.74 | CYP1A2 (0.49) | CYP1A2KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL27654447 | 0.73 | CYP1A2 (0.51) | CYP1A2KMT2AALDH1A1MAPTMAPK10 | |
| SCHEMBL299834 | 0.69 | NPC1 (0.42) | CYP1A2KMT2AALDH1A1MAPTMAPK10 | |
| SCHEMBL2243516 | 0.68 | KDM4E (0.52) | CYP1A2KMT2AALDH1A1MAPTMAPK10 | |
| SCHEMBL5568496 | 0.66 | NPC1 (0.43) | CYP1A2KMT2AALDH1A1MAPTMAPK10 | |
| SCHEMBL28183808 | 0.65 | CYP1A2 (0.70) | CYP1A2KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL14099190 | 0.64 | CYP1A2 (0.53) | CYP1A2KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL30198446 | 0.64 | CYP1A2 (0.60) | CYP1A2ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL30527184 | 0.64 | CYP1A2 (0.60) | CYP1A2ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL1672650 | 0.64 | CYP1A2 (0.60) | CYP1A2ALDH1A1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392315-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002100410-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-12-19 | — | — | WO | disclosed |