Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 4/20 | 0.58 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.48 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.48 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.48 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.48 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.48 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.48 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6705864 | 0.88 | CHRM4 (0.66) | OPRL1CHRM4CHRM1MCHR1CYP2D6 | |
| SCHEMBL6222386 | 0.85 | OPRL1 (0.58) | OPRL1CHRM4OPRM1KDM4EALDH1A1 | |
| SCHEMBL6704754 | 0.77 | MCHR1 (0.52) | KDM4EALDH1A1CHRM2CHRM1CHRM3 | |
| SCHEMBL3877227 | 0.76 | MCHR1 (0.79) | CHRM4KDM4EALDH1A1CHRM1MCHR1 | |
| SCHEMBL6705783 | 0.73 | CHRM4 (0.70) | OPRL1CHRM4OPRM1KDM4EALDH1A1 | |
| SCHEMBL4778246 | 0.73 | OPRL1 (0.78) | OPRL1OPRM1 | |
| SCHEMBL4808830 | 0.73 | OPRL1 (0.55) | OPRL1CHRM4OPRM1S1PR2 | |
| SCHEMBL29432121 | 0.72 | CHRM4 (1.00) | OPRL1CHRM4CHRM2CHRM1CHRM5 | |
| SCHEMBL6705907 | 0.72 | PRMT5 (0.52) | KDM4EALDH1A1CHRM1MCHR1CYP2D6 | |
| Hydrochloric Acid SCHEMBL8892803 | 0.71 | CHRM4 (0.51) | OPRL1CHRM4OPRM1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040242572-A1 | New carboxamide compounds having melanin concentrating hormone antagonistic activity, pharmaceutical preparations comprising these compounds and process for their manufacture | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242572-A1 | New carboxamide compounds having melanin concentrating hormone antagonistic activity, pharmaceutical preparations comprising these compounds and process for their manufacture | MCHR2, MCHR1, NPY1R | OPRL1 39/4885CHRM4 467/4885OPRM1 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.