Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.48 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | ACP3 | P15309 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | IAPP | P10997 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7340131 | 0.91 | TDP1 (0.58) | MTNR1ATDP1GPR84CDYLP2RX7 | |
| SCHEMBL9404001 | 0.84 | MTNR1A (0.58) | MTNR1ATDP1GPR84CDYLP2RX7 | |
| SCHEMBL6282199 | 0.82 | MTNR1A (0.50) | MTNR1ATDP1GPR84CDYLP2RX7 | |
| SCHEMBL8400463 | 0.81 | IAPP (0.58) | MTNR1ATDP1GPR84CDYLP2RX7 | |
| SCHEMBL13227199 | 0.80 | CDYL (0.53) | MTNR1ATDP1GPR84CDYLP2RX7 | |
| SCHEMBL30307853 | 0.79 | TDP1 (0.67) | MTNR1ATDP1GPR84CDYLKDM4E | |
| SCHEMBL1566760 | 0.79 | TDP1 (0.56) | MTNR1ATDP1GPR84CDYLP2RX7 | |
| SCHEMBL1218835 | 0.79 | TDP1 (0.67) | MTNR1ATDP1GPR84CDYLKDM4E | |
| SCHEMBL129188 | 0.78 | CYP1A2 (0.54) | MTNR1ATDP1ACP3CYP1A2NQO2 | |
| SCHEMBL14608998 | 0.78 | MTNR1A (0.49) | MTNR1ATDP1GPR84CDYLP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392315-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002100410-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-12-19 | — | — | WO | disclosed |