⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4237662 | 0.97 | — | — | |
| SCHEMBL30812390 | 0.74 | — | — | |
| SCHEMBL1760200 | 0.70 | — | — | |
| Bromide SCHEMBL8931675 | 0.68 | — | — | |
| SCHEMBL2297737 | 0.67 | — | — | |
| SCHEMBL30160680 | 0.65 | — | — | |
| SCHEMBL5879546 | 0.65 | — | — | |
| SCHEMBL31662773 | 0.65 | — | — | |
| SCHEMBL7447410 | 0.63 | — | — | |
| SCHEMBL1515000 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 335 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115772114-B | Method for synthesizing 2, 3-dihydropyridinone by one-pot catalysis of iodopyridinium salt | 成都理工大学 | 2024-09-06 | — | — | CN | claimed |
| CN-115710281-B | Isoxazolo [5,4-b ] pyridine FLT3 inhibitor and preparation method and application thereof | 南京中医药大学 | 2024-05-17 | — | — | CN | claimed |
| CN-117836297-A | (S) -1- (5- ((pyridin-3-yl) thio) pyrazin-2-yl) -4'H,6' H-spiro [ piperidine-4, 5 '-pyrrolo [1,2-B ] pyrazol ] -4' -amine derivatives and similar compounds as SHP2 inhibitors for the treatment of, for example, cancer | 国家化学成分收集和筛选中心 | 2024-04-05 | — | — | CN | claimed |
| CN-115368357-B | Synthesis method of calcium channel enhancer SAK3 intermediate | 南京市天铭医药科技有限公司 | 2023-09-29 | — | — | CN | claimed |
| CN-115772114-A | Method for synthesizing 2, 3-dihydropyridone by one-pot method under catalysis of iodopyridinium salt | 成都理工大学 | 2023-03-10 | — | — | CN | claimed |
| CN-115710281-A | Isoxazolo [5,4-b ] pyridine FLT 3inhibitor and preparation method and application thereof | 南京中医药大学 | 2023-02-24 | — | — | CN | claimed |
| CN-110678472-B | 2-oxothiazole derivatives as A2A inhibitors and compounds for the treatment of cancer | 伊忒欧斯比利时股份公司 | 2023-01-24 | — | — | CN | claimed |
| WO-2023280132-A1 | CRYSTAL FORM OF OXODIHYDROIMIDAZOPYRIDINE COMPOUND AND PREPARATION METHOD THEREFOR | 苏州晶云药物科技股份有限公司 | 2023-01-12 | — | — | WO | claimed |
| CN-115368357-A | Synthetic method of calcium channel enhancer SAK3 intermediate | 南京市天铭医药科技有限公司 | 2022-11-22 | — | — | CN | claimed |
| EP-3802547-A1 | PROCESS FOR PRODUCING COMPOUNDS CONTAINING AN OXAZOLOPYRIDINONE FUNCTIONAL GROUP | Biocidal Alternative Solutions (BE) | 2021-04-14 | — | — | EP | claimed |
| US-20100204236-A1 | Substituted imidazoles as bombesin receptor subtype-3 modulators | MERCK SHARP & DOHME CORP. | 2010-08-12 | — | — | US | claimed |
| EP-2083623-A1 | SUBSTITUTED IMIDAZOLES AS BOMBESIN RECEPTOR SUBTYPE-3 MODULATORS | Merck & Co., Inc. (US) | 2009-08-05 | — | — | EP | claimed |
| EP-1729772-A4 | HETEROARYL PIPERIDINE GLYCINE TRANSPORTER INHIBITORS | MERCK & CO INC (US) | 2009-05-27 | — | — | EP | claimed |
| WO-2008051405-A1 | SUBSTITUTED IMIDAZOLES AS BOMBESIN RECEPTOR SUBTYPE-3 MODULATORS | MERCK & CO., INC. (US) | 2008-05-02 | — | — | WO | claimed |
| CN-101160307-A | Benzoxazole carboxamides for the treatment of CINV and IBS-D | AMR TECHNOLOGY INC (US) | 2008-04-09 | — | — | CN | claimed |
| US-20070254880-A1 | Heteroaryl Piperidine Glycine Transporter Inhibitors | MERCK SHARP & DOHME LLC | 2007-11-01 | — | — | US | claimed |
| CN-1933836-A | Heteroaryl piperidine glycine transporter inhibitors | MERCK & CO INC (US) | 2007-03-21 | — | — | CN | claimed |
| EP-1729772-A2 | HETEROARYL PIPERIDINE GLYCINE TRANSPORTER INHIBITORS | Merck and Co., Inc. (US) | 2006-12-13 | — | — | EP | claimed |
| WO-2005094514-A2 | HETEROARYL PIPERIDINE GLYCINE TRANSPORTER INHIBITORS | MERCK & CO., INC. (US) | 2005-10-13 | — | — | WO | claimed |
| CN-1468241-A | Heterocyclic compounds as ligands of the gabaa receptor | — | 2004-01-14 | — | — | CN | claimed |