SCHEMBL670924

SCHEMBL670924

Cc1ccccc1-n1cc(-n2c(C)c(Sc3cccc(C(=O)O)c3)c3ccc(Cl)c(F)c32)cn1

nearest known ligand 0.54

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 20/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL671310 0.93 ENPP2 (0.56) ENPP2
SCHEMBL673693 0.89 ENPP2 (0.59) ENPP2
SCHEMBL672525 0.89 ENPP2 (0.55) ENPP2
SCHEMBL671324 0.87 ENPP2 (0.70) ENPP2
SCHEMBL671940 0.85 ENPP2 (0.64) ENPP2
SCHEMBL673060 0.85 ENPP2 (0.56) ENPP2
SCHEMBL672607 0.85 ENPP2 (0.56) ENPP2
SCHEMBL670279 0.84 ENPP2 (0.76) ENPP2
SCHEMBL671760 0.84 ENPP2 (0.64) ENPP2
SCHEMBL671875 0.84 ENPP2 (0.56) ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2606031-A2 AUTOTAXIN INHIBITORS AND USES THEREOF Amira Pharmaceuticals, Inc. (US) 2013-06-26 EP claimed
WO-2012024620-A2 AUTOTAXIN INHIBITORS AND USES THEREOF AMIRA PHARMACEUTICALS, INC. (US) 2012-02-23 WO claimed