SCHEMBL6709274

SCHEMBL6709274

CC(OC=O)C1CCCN1

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 7/20 0.33
SLC6A2 P23975 5/20 0.33
SLC6A4 P31645 4/20 0.33
DHFR P00374 1/20 0.32
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27650831 0.98 SLC6A2 (0.33) SLC6A3SLC6A2SLC6A4ALDH1A1LMNA
Hydrochloric Acid SCHEMBL27916528 0.98 SLC6A2 (0.33) SLC6A3SLC6A2SLC6A4ALDH1A1LMNA
SCHEMBL5254752 0.94 SLC6A3 (0.39) SLC6A3SLC6A2SLC6A4DHFRALDH1A1
SCHEMBL17377297 0.77 SLC6A3 (0.38) SLC6A3SLC6A2SLC6A4DHFR
SCHEMBL28094899 0.77
SCHEMBL27952382 0.77
SCHEMBL5535061 0.76
SCHEMBL23603002 0.75
SCHEMBL15818137 0.75
SCHEMBL4838694 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114409584-A Preparation method of 1-methylpyrrolidine-2-formaldehyde 重庆医药高等专科学校 2022-04-29 CN claimed
CN-114409584-A Preparation method of 1-methylpyrrolidine-2-formaldehyde 重庆医药高等专科学校 2022-04-29 CN disclosed
CN-114409584-A Preparation method of 1-methylpyrrolidine-2-formaldehyde 重庆医药高等专科学校 2022-04-29 CN disclosed
CN-105399698-A Aromatic heterocyclic derivatives and applications of aromatic heterocyclic derivatives in medicines GUANGDONG HEC PHARMACEUTICAL 2016-03-16 CN disclosed
CN-101622258-B Bicyclic oxomorpholine derivatives EISAI R&D MAN CO LTD 2012-06-13 CN disclosed
CN-1964970-B Inhibitors of iap NOVARTIS AG 2011-08-03 CN disclosed
CN-102036984-A Novel compounds as cannabinoid receptor ligands ABBOTT LAB 2011-04-27 CN disclosed
CN-1795193-B N-acyl nitrogen heterocyles as ligands of peroxisome proliferator-activated receptors NOVARTIS AG 2010-08-18 CN disclosed
CN-101622258-A Bicyclic oxomorpholine derivatives EISAI R&D MAN CO LTD 2010-01-06 CN disclosed
CN-1964970-A Inhibitors of IAP NOVARTIS AG (CH) 2007-05-16 CN disclosed
CN-1795193-A N-acyl nitrogen heterocyles as ligands of peroxisome proliferator-activated receptors NOVARTIS AG (CH) 2006-06-28 CN disclosed
CN-1671379-A Hydrazinopyrazole derivatives and their use as therapeutic agents QUADRA LOGIC TECH INC (CA) 2005-09-21 CN disclosed
EP-1392315-A1 METHODS OF TREATING ALZHEIMER'S DISEASE Elan Pharmaceuticals, Inc. (US) 2004-03-03 EP disclosed
WO-2002100410-A1 METHODS OF TREATING ALZHEIMER'S DISEASE ELAN PHARMACEUTICALS, INC. (US) 2002-12-19 WO disclosed