Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 7/20 | 0.53 |
| ▸ | PRKCI | P41743 | 1/20 | 0.45 |
| ▸ | QPCT | Q16769 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5668743 | 0.89 | TBXAS1 (0.42) | TBXAS1PRKCIQPCT | |
| SCHEMBL78110 | 0.86 | — | — | |
| SCHEMBL9253280 | 0.86 | TBXAS1 (0.71) | TBXAS1PRKCI | |
| Bromide SCHEMBL28608395 | 0.84 | TBXAS1 (0.68) | TBXAS1PRKCI | |
| Hydrochloric Acid SCHEMBL2674176 | 0.84 | TBXAS1 (0.68) | TBXAS1PRKCIMEN1KMT2AATM | |
| Fluoride SCHEMBL31379738 | 0.84 | TBXAS1 (0.68) | TBXAS1PRKCI | |
| Water SCHEMBL2854772 | 0.84 | TBXAS1 (0.68) | TBXAS1PRKCI | |
| Hydrochloric Acid SCHEMBL4781930 | 0.84 | TBXAS1 (0.68) | TBXAS1PRKCIMEN1KMT2AATM | |
| Iodide SCHEMBL29834228 | 0.84 | TBXAS1 (0.68) | TBXAS1PRKCI | |
| 1-Methylimidazole SCHEMBL29053358 | 0.81 | TBXAS1 (0.59) | TBXAS1PRKCIQPCTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1248615-A4 | THIAZOLE, IMIDAZOLE AND OXAZOLE COMPOUNDS AND TREATMENTS OF DISORDERS ASSOCIATED WITH PROTEIN AGING | ALTEON INC (US) | 2004-08-04 | — | — | EP | disclosed |
| EP-1248615-A1 | THIAZOLE, IMIDAZOLE AND OXAZOLE COMPOUNDS AND TREATMENTS OF DISORDERS ASSOCIATED WITH PROTEIN AGING | Alteon, Inc. (US) | 2002-10-16 | — | — | EP | disclosed |
| WO-2001052847-A1 | THIAZOLE, IMIDAZOLE AND OXAZOLE COMPOUNDS AND TREATMENTS OF DISORDERS ASSOCIATED WITH PROTEIN AGING | ALTEON, INC. (US) | 2001-07-26 | — | — | WO | disclosed |