Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 19/20 | 0.73 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14963286 | 0.86 | SSTR5 (0.81) | SSTR5 | |
| SCHEMBL10284310 | 0.84 | SSTR5 (1.00) | SSTR5 | |
| SCHEMBL14963280 | 0.78 | SSTR5 (0.82) | SSTR5 | |
| SCHEMBL10283868 | 0.77 | SSTR5 (1.00) | SSTR5 | |
| SCHEMBL14957315 | 0.72 | SSTR5 (1.00) | SSTR5 | |
| SCHEMBL14963278 | 0.72 | SSTR5 (0.82) | SSTR5 | |
| SCHEMBL14963437 | 0.71 | SSTR5 (0.70) | SSTR5 | |
| SCHEMBL11359525 | 0.71 | SIGMAR1 (0.56) | SSTR5 | |
| SCHEMBL14963285 | 0.71 | SSTR5 (0.80) | SSTR5 | |
| SCHEMBL10283858 | 0.71 | SSTR5 (1.00) | SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2605658-A1 | SPIROXAZOLIDINONE COMPOUNDS | Merck Sharp & Dohme Corp. (US) | 2013-06-26 | — | — | EP | disclosed |
| WO-2012024183-A1 | SPIROXAZOLIDINONE COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2012-02-23 | — | — | WO | disclosed |