Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | TSHR | P16473 | 7/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16248492 | 0.92 | ALDH1A1 (0.51) | ALDH1A1TSHRTDP1L3MBTL1MAPK1 | |
| Phthalic Acid SCHEMBL7766315 | 0.86 | ALDH1A1 (0.45) | ALDH1A1TSHRTDP1MAPK1HIF1A | |
| SCHEMBL28439910 | 0.85 | ALDH1A1 (0.56) | ALDH1A1TSHRTDP1L3MBTL1MAPK1 | |
| SCHEMBL8423222 | 0.83 | ALDH1A1 (0.57) | ALDH1A1TSHRTDP1L3MBTL1MAPK1 | |
| Phthalic Acid SCHEMBL10953701 | 0.82 | ALDH1A1 (0.41) | ALDH1A1TSHRTDP1MAPK1HIF1A | |
| SCHEMBL30477175 | 0.82 | ALDH1A1 (0.53) | ALDH1A1TSHRTDP1L3MBTL1MAPK1 | |
| SCHEMBL22979070 | 0.80 | TSHR (0.53) | ALDH1A1TSHRTDP1L3MBTL1MAPK1 | |
| SCHEMBL13497558 | 0.79 | ALDH1A1 (0.47) | ALDH1A1TSHRTDP1L3MBTL1MAPK1 | |
| SCHEMBL21561621 | 0.79 | MAPT (0.44) | ALDH1A1TSHRMAPK1HIF1ALMNA | |
| SCHEMBL21561618 | 0.77 | MAPT (0.42) | ALDH1A1TSHRMAPK1HIF1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6806042-B2 | PHOTOGRAPHIC FILMS COMPRISNG SUPPORTS HAVING RED, GREEN AND BLUE SENSITIVE SILVER HALIDE EMULSIONS, AND CYAN, MAGENTA AND YELLOW COUPLERS RESPECTIVELY; IMAGES | AGFA-GEVAERT (BE) | 2004-10-19 | — | — | US | disclosed |
| US-20040023171-A1 | Colour photographic print material | AGFA-GEVAERT N.V. (BELGIUM) | 2004-02-05 | — | — | US | disclosed |
| EP-1380893-A2 | Colour photographic print material | Agfa-Gevaert (BE) | 2004-01-14 | — | — | EP | disclosed |
| EP-0280238-B2 | Silver halide color photographic photosensitive materials | FUJI PHOTO FILM CO LTD (JP) | 2001-05-30 | — | — | EP | disclosed |
| EP-0280238-B1 | SILVER HALIDE COLOR PHOTOGRAPHIC PHOTOSENSITIVE MATERIALS | Fuji Photo Film Co., Ltd. (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-4857449-A | Silver halide color photographic photosensitive materials | FUJI PHOTO FILM CO., LTD. (JP) | 1989-08-15 | — | — | US | disclosed |
| EP-0280238-A2 | Silver halide color photographic photosensitive materials | Fuji Photo Film Co., Ltd. (JP) | 1988-08-31 | — | — | EP | disclosed |
| US-4268609-A | Process for preparing photosensitive lithographic printing plate precursor | FUJI PHOTO FILM CO., LTD. (JP) | 1981-05-19 | — | — | US | disclosed |