Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SSTR1 | P30872 | 3/20 | 0.44 |
| ▸ | SSTR3 | P32745 | 3/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29409629 | 0.85 | KMT2A (0.44) | ALDH1A1LMNAMAPTSMN1; SMN2SSTR1 | |
| SCHEMBL22589628 | 0.85 | KMT2A (0.44) | ALDH1A1LMNAMAPTSMN1; SMN2SSTR1 | |
| SCHEMBL29881725 | 0.85 | KMT2A (0.44) | ALDH1A1LMNAMAPTSMN1; SMN2SSTR1 | |
| SCHEMBL6712704 | 0.84 | FABP5 (0.44) | SLC18A3ALDH1A1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL7138685 | 0.83 | MAPT (0.65) | ALDH1A1LMNAMAPTSMN1; SMN2SSTR1 | |
| SCHEMBL25279722 | 0.82 | SSTR1 (0.39) | SLC18A3ALDH1A1SSTR1SSTR3SIGMAR1 | |
| SCHEMBL28707687 | 0.82 | KMT2A (0.41) | ALDH1A1LMNAMAPTSMN1; SMN2SSTR1 | |
| SCHEMBL15747761 | 0.81 | SMN1; SMN2 (0.58) | LMNAMAPTSMN1; SMN2SIGMAR1HTT | |
| SCHEMBL31372025 | 0.80 | CYP1A2 (0.45) | MAPTSSTR1SSTR3KMT2ACYP1A2 | |
| SCHEMBL13327274 | 0.78 | POLB (0.52) | ALDH1A1LMNAMAPTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092524-A1 | Novel aminophenyl piperazine or aminophenyl piperidine derivatives inhibiting prenyl transferase proteins and method for preparing same | PIERRE FABRE MEDICAMENT (FR) | 2004-05-13 | — | — | US | disclosed |
| EP-1324999-A1 | NOVEL AMINOPHENYL PIPERAZINE OR AMINOPHENYL PIPERIDINE DERIVATIVES INHIBITING PRENYL TRANSFERASE PROTEINS AND METHODS FOR PREPARING SAME | PIERRE FABRE MEDICAMENT (FR) | 2003-07-09 | — | — | EP | disclosed |
| WO-2002030927-A1 | NOVEL AMINOPHENYL PIPERAZINE OR AMINOPHENYL PIPERIDINE DERIVATIVES INHIBITING PRENYL TRANSFERASE PROTEINS AND METHODS FOR PREPARING SAME | PIERRE FABRE MEDICAMENT (FR) | 2002-04-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092524-A1 | Novel aminophenyl piperazine or aminophenyl piperidine derivatives inhibiting prenyl transferase proteins and method for preparing same | CBR3, CBR1, HCCS | FAAH 2607/4885SLC18A3 2727/4885ALDH1A1 3031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.