Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | SSTR1 | P30872 | 3/20 | 0.61 |
| ▸ | SSTR3 | P32745 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14599486 | 0.84 | GAA (0.53) | MAPTALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL6711014 | 0.83 | FAAH (0.44) | MAPTALDH1A1LMNASMN1; SMN2SSTR1 | |
| SCHEMBL4652078 | 0.83 | MAPT (0.46) | MAPTALDH1A1LMNASMN1; SMN2SSTR1 | |
| SCHEMBL1919737 | 0.83 | NPC1 (0.46) | MAPTALDH1A1LMNASMN1; SMN2SSTR1 | |
| SCHEMBL3853309 | 0.82 | MAPT (0.45) | MAPTALDH1A1LMNASMN1; SMN2SSTR1 | |
| SCHEMBL29881725 | 0.82 | KMT2A (0.44) | MAPTALDH1A1LMNASMN1; SMN2SSTR1 | |
| SCHEMBL22589628 | 0.82 | KMT2A (0.44) | MAPTALDH1A1LMNASMN1; SMN2SSTR1 | |
| SCHEMBL29409629 | 0.82 | KMT2A (0.44) | MAPTALDH1A1LMNASMN1; SMN2SSTR1 | |
| SCHEMBL22397770 | 0.82 | POLB (0.52) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL13327274 | 0.82 | POLB (0.52) | MAPTALDH1A1LMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1324999-A1 | NOVEL AMINOPHENYL PIPERAZINE OR AMINOPHENYL PIPERIDINE DERIVATIVES INHIBITING PRENYL TRANSFERASE PROTEINS AND METHODS FOR PREPARING SAME | PIERRE FABRE MEDICAMENT (FR) | 2003-07-09 | — | — | EP | disclosed |
| WO-2002030927-A1 | NOVEL AMINOPHENYL PIPERAZINE OR AMINOPHENYL PIPERIDINE DERIVATIVES INHIBITING PRENYL TRANSFERASE PROTEINS AND METHODS FOR PREPARING SAME | PIERRE FABRE MEDICAMENT (FR) | 2002-04-18 | — | — | WO | disclosed |