SCHEMBL6711344

SCHEMBL6711344

O=C(C/C=C/CC(=O)OCc1ccccc1)OCc1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.66
MAPK1 P28482 1/20 0.66
L3MBTL1 Q9Y468 1/20 0.66
TDP1 Q9NUW8 3/20 0.55
SLC6A2 P23975 1/20 0.55
SLC6A3 Q01959 1/20 0.55
KMT2A Q03164 1/20 0.55
HCAR2 Q8TDS4 1/20 0.55
LMNA P02545 4/20 0.51
CDC25B P30305 1/20 0.49
CA12 O43570 2/20 0.47
CA9 Q16790 2/20 0.47
AKR1B10 O60218 1/20 0.47
AKR1B1 P15121 1/20 0.47
CA4 P22748 1/20 0.47
CA6 P23280 1/20 0.47
CA5A P35218 1/20 0.47
CA7 P43166 1/20 0.47
CA14 Q9ULX7 1/20 0.47
CA5B Q9Y2D0 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6650547 1.00 ALDH1A1 (0.66) ALDH1A1MAPK1L3MBTL1TDP1SLC6A2
SCHEMBL7324468 0.91 ALDH1A1 (0.56) ALDH1A1MAPK1L3MBTL1TDP1SLC6A2
SCHEMBL10578902 0.89 ALDH1A1 (0.58) ALDH1A1MAPK1L3MBTL1TDP1SLC6A2
SCHEMBL10702738 0.89 ALDH1A1 (0.58) ALDH1A1MAPK1L3MBTL1TDP1SLC6A2
SCHEMBL9568209 0.88 ALDH1A1 (0.66) ALDH1A1MAPK1L3MBTL1TDP1SLC6A2
SCHEMBL31362046 0.88 HCAR2 (0.65) ALDH1A1MAPK1L3MBTL1TDP1SLC6A2
SCHEMBL2562532 0.86 ALDH1A1 (0.63) ALDH1A1MAPK1L3MBTL1TDP1SLC6A2
SCHEMBL10920046 0.86 ALDH1A1 (0.54) ALDH1A1MAPK1L3MBTL1TDP1SLC6A2
Bromide SCHEMBL8436689 0.86 ALDH1A1 (0.50) ALDH1A1MAPK1L3MBTL1TDP1SLC6A2
SCHEMBL27450079 0.86 ALDH1A1 (0.50) ALDH1A1MAPK1L3MBTL1TDP1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6828464-B2 Preparation of cyclopentenones BASF AKTIENGESELLSCHAFT (DE) 2004-12-07 US disclosed
US-20040102655-A1 Preparation of cyclopentenoes BASF AKTIENGESELLSCHAFT (DE) 2004-05-27 US disclosed
EP-0016150-B1 PROCESS FOR THE CARBONYLATION OF DIOLEFINS POLYMER SCIENCES CORPORATION (US) 1982-07-28 EP disclosed
US-4259519-A Process for the carbonylation of diolefins POLYMER SCIENCES CORPORATION (US) 1981-03-31 US disclosed
EP-0016150-A4 Process for the carbonylation of diolefins. POLYMER SCIENCES CORP (US) 1980-10-09 EP disclosed
EP-0016150-A1 Process for the carbonylation of diolefins. POLYMER SCIENCES CORP (US) 1980-10-01 EP disclosed
WO-1980000250-A1 PROCESS FOR THE CARBONATION OF DIOLEFINS POLYMER SCIENCES CORP (US) 1980-02-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040102655-A1 Preparation of cyclopentenoes CYP17A1, CYP2F1, CYP2S1 ALDH1A1 389/4885MAPK1 1129/4885L3MBTL1 4730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.