Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | RAF1 | P04049 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13165061 | 0.84 | SMN1; SMN2 (0.64) | SMN1; SMN2MEN1KMT2ARAF1LMNA | |
| SCHEMBL1622168 | 0.76 | LIMK1 (1.00) | SMN1; SMN2MEN1KMT2ARAF1LMNA | |
| SCHEMBL6911943 | 0.75 | LIMK1 (0.66) | SMN1; SMN2MEN1KMT2ARAF1LMNA | |
| SCHEMBL13165134 | 0.73 | SMN1; SMN2 (0.65) | SMN1; SMN2MEN1KMT2ARAF1LMNA | |
| SCHEMBL13164961 | 0.73 | IRAK4 (0.72) | SMN1; SMN2MEN1KMT2ARAF1LMNA | |
| SCHEMBL10325795 | 0.72 | IRAK4 (0.74) | SMN1; SMN2MEN1KMT2ARAF1LMNA | |
| SCHEMBL19523694 | 0.72 | IRAK4 (0.74) | SMN1; SMN2MEN1KMT2ARAF1LMNA | |
| SCHEMBL1604779 | 0.72 | LIMK1 (0.61) | SMN1; SMN2MEN1KMT2ARAF1LMNA | |
| SCHEMBL13644138 | 0.72 | LIMK1 (0.61) | SMN1; SMN2MEN1KMT2ARAF1LMNA | |
| SCHEMBL6642198 | 0.72 | LIMK1 (0.61) | SMN1; SMN2MEN1KMT2ARAF1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040053977-A1 | Medicinal uses of hydrazones | ALMSTEAD JI-IN KIM (US) | 2004-03-18 | — | — | US | disclosed |
| US-6660737-B2 | Antihypoxic agents | THE PROCTER & GAMBLE COMPANY | 2003-12-09 | — | — | US | disclosed |
| US-20030092716-A1 | Medicinal uses of hydrazones | THE PROCTER & GAMBLE COMPANY | 2003-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053977-A1 | Medicinal uses of hydrazones | PGF, VEGFA, TEK | SMN1; SMN2 2892/4885MEN1 1753/4885KMT2A 3683/4885 |
| US-20030092716-A1 | Medicinal uses of hydrazones | EPOR, VEGFA, HIF1A | SMN1; SMN2 2163/4885MEN1 1904/4885KMT2A 4156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.