⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4289473 | 0.78 | — | — | |
| SCHEMBL9863688 | 0.78 | — | — | |
| SCHEMBL4619439 | 0.76 | — | — | |
| SCHEMBL17117691 | 0.76 | — | — | |
| SCHEMBL27337642 | 0.76 | — | — | |
| SCHEMBL29586784 | 0.76 | — | — | |
| SCHEMBL9709613 | 0.76 | — | — | |
| SCHEMBL28720266 | 0.76 | — | — | |
| SCHEMBL2873058 | 0.76 | ALDH1A1 (0.43) | — | |
| SCHEMBL7340031 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040106564-A1 | Use of slpi for treating chronic inflammatory intestinal diseases | VIVOTEC BIOMEDICAL TECHNOLOGIES GMBH (DE) | 2004-06-03 | — | — | US | disclosed |
| EP-1353680-A2 | USE OF SLPI FOR TREATING CHRONIC INFLAMMATORY INTESTINAL DISEASES | Vivotec Biomedical Technologies GmbH (DE) | 2003-10-22 | — | — | EP | disclosed |
| WO-2002056900-A2 | USE OF SLPI FOR TREATING CHRONIC INFLAMMATORY INTESTINAL DISEASES | VIVOTEC BIOMEDICAL TECHNOLOGIES GMBH (DE) | 2002-07-25 | — | — | WO | disclosed |