SCHEMBL6711780

SCHEMBL6711780

CC(Br)c1cccc2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.50
ALDH1A1 P00352 7/20 0.50
MAPK1 P28482 6/20 0.50
L3MBTL1 Q9Y468 5/20 0.50
SMN1; SMN2 Q16637 5/20 0.50
EGFR P00533 4/20 0.50
RAB9A P51151 4/20 0.50
TDP1 Q9NUW8 3/20 0.50
LMNA P02545 2/20 0.50
PABPC1 P11940 1/20 0.50
ADORA2A P29274 1/20 0.50
NSD2 O96028 1/20 0.50
KMT2A Q03164 6/20 0.46
MEN1 O00255 5/20 0.46
CDC25B P30305 1/20 0.46
MAOA P21397 5/20 0.45
NPC1 O15118 3/20 0.44
CYP3A4 P08684 2/20 0.44
TSHR P16473 1/20 0.44
CASP3 P42574 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7915851 0.84 ADORA2A (0.53) MAPTALDH1A1MAPK1L3MBTL1SMN1; SMN2
SCHEMBL10433548 0.84 ADORA2A (0.53) MAPTALDH1A1MAPK1L3MBTL1SMN1; SMN2
SCHEMBL10940842 0.81 ALDH1A1 (0.50) MAPTALDH1A1MAPK1L3MBTL1SMN1; SMN2
SCHEMBL526407 0.78 TSHR (0.48) MAPTALDH1A1MAPK1L3MBTL1SMN1; SMN2
SCHEMBL11294914 0.76 ADORA2A (0.59) MAPTALDH1A1MAPK1L3MBTL1SMN1; SMN2
SCHEMBL12769790 0.76 NPC1 (0.49) MAPTALDH1A1MAPK1L3MBTL1SMN1; SMN2
SCHEMBL14199926 0.76 MEN1 (0.50) MAPTALDH1A1MAPK1L3MBTL1SMN1; SMN2
SCHEMBL30020965 0.76 MAPT (0.49) MAPTALDH1A1MAPK1L3MBTL1SMN1; SMN2
SCHEMBL21840820 0.75 MEN1 (0.48) MAPTALDH1A1MAPK1L3MBTL1SMN1; SMN2
SCHEMBL8772052 0.75 ALDH1A1 (0.45) MAPTALDH1A1MAPK1L3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1025608-C Fluoro-naphthacenediones, their glycosilated derivatives and their manufacture procedures MENARINI FARMA IND (IT) 1994-08-10 CN claimed
CN-1052659-A New fluoro-tetracene diketone, its glycosidation derivant and preparation method thereof MENARINI FARMA IND (IT) 1991-07-03 CN claimed
CN-105764885-B The production method of acid and free-radical generating agent and acid and free radical 富士胶片和光纯药株式会社 2018-11-09 CN disclosed
US-6756130-B1 OXYGEN ABSORBING FOOD PACKAGING; ETHYLENE-ALKYLACRYLATE-UNSATURATED EPOXIDE DERIVATIZED WITH SUCH AS 2-CARBOXY-ANTHRAQUINONE; FOOD PACKAGING ATOFINA (FR) 2004-06-29 US disclosed
US-20040077786-A1 Oxygen absorbent films and structures comprising same ATOFINA (FR) 2004-04-22 US disclosed
EP-1234000-B1 POLYOLEFIN FILMS CONTAINING GRAFTED QUINONES AND STRUCTURES COMPRISING SAME ATOFINA (FR) 2003-07-30 EP disclosed
EP-1285025-A1 OXYGEN ABSORBENT FILMS AND STRUCTURES COMPRISING SAME Atofina (FR) 2003-02-26 EP disclosed
WO-2001088023-A1 OXYGEN ABSORBENT FILMS AND STRUCTURES COMPRISING SAME ATOFINA (FR) 2001-11-22 WO disclosed
CN-1025608-C Fluoro-naphthacenediones, their glycosilated derivatives and their manufacture procedures MENARINI FARMA IND (IT) 1994-08-10 CN disclosed
CN-1052659-A New fluoro-tetracene diketone, its glycosidation derivant and preparation method thereof MENARINI FARMA IND (IT) 1991-07-03 CN disclosed