Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 9/20 | 0.51 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.49 |
| ▸ | TERT | O14746 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8080324 | 0.91 | DNM1 (0.50) | PAOXEPHX2DNM1PPARAFAAH | |
| SCHEMBL4900100 | 0.91 | DNM1 (0.50) | PAOXEPHX2DNM1PPARAFAAH | |
| SCHEMBL28065455 | 0.91 | DNM1 (0.50) | PAOXEPHX2DNM1PPARAFAAH | |
| Acetic Acid SCHEMBL28970281 | 0.91 | PAOX (0.66) | PAOXDNM1KMT2A | |
| Acetic Acid SCHEMBL1427140 | 0.87 | EPHX2 (0.59) | EPHX2DNM1TERTMAPTBLM | |
| Acetic Acid SCHEMBL1427139 | 0.87 | EPHX2 (0.59) | EPHX2DNM1TERTMAPTBLM | |
| SCHEMBL10008591 | 0.86 | TRPV1 (0.49) | MAPTBLMKMT2A | |
| SCHEMBL10008594 | 0.86 | TRPV1 (0.49) | MAPTBLMKMT2A | |
| Acetic Acid SCHEMBL8337232 | 0.85 | EPHX2 (0.55) | EPHX2TERTMAPTBLMHSD17B10 | |
| Acetic Acid SCHEMBL8337241 | 0.85 | EPHX2 (0.55) | EPHX2TERTMAPTBLMHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004096942-A1 | AMIDOAMINE SALT-BASED VISCOSIFYING AGENTS AND METHOD OF USE | TOMAH PRODUCTS, INC. (US) | 2004-11-11 | — | — | WO | disclosed |