SCHEMBL671410

SCHEMBL671410

CNC(=O)C1CCCCN1CC(=O)NCC(=O)N(C)c1ccc(Cl)c(COc2cccc3c2nc(OC)n3Cc2ccccn2)c1Cl

nearest known ligand 0.62

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BDKRB2 P30411 19/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL671181 0.92 BDKRB2 (0.61) BDKRB2
SCHEMBL671864 0.92 BDKRB2 (0.61) BDKRB2
SCHEMBL10072383 0.89 BDKRB2 (0.64) BDKRB2
SCHEMBL10072366 0.88 BDKRB2 (0.67) BDKRB2
SCHEMBL658297 0.88 BDKRB2 (0.61) BDKRB2
SCHEMBL658296 0.88 BDKRB2 (0.61) BDKRB2
SCHEMBL661033 0.86 BDKRB2 (0.62) BDKRB2
SCHEMBL660502 0.86 BDKRB2 (0.62) BDKRB2
SCHEMBL10072516 0.86 BDKRB2 (0.64) BDKRB2
SCHEMBL10072586 0.86 BDKRB2 (0.61) BDKRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012024419-A2 BRADYKININ RECEPTOR AGONISTS AND USES THEREOF TO TREAT OCULAR HYPERTENSION AND GLAUCOMA ALCON RESEARCH, LTD. (US) 2012-02-23 WO disclosed