Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | F10 | P00742 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.32 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | ADK | P55263 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | CKS1B | P61024 | 1/20 | 0.32 |
| ▸ | SKP1 | P63208 | 1/20 | 0.32 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6719151 | 0.84 | F10 (0.44) | MEN1KMT2AF10SMN1; SMN2MAPT | |
| SCHEMBL6712514 | 0.78 | F10 (0.41) | KMT2AF10SMN1; SMN2NPSR1 | |
| SCHEMBL6712468 | 0.77 | F10 (0.40) | F10 | |
| SCHEMBL6712477 | 0.76 | KCNH2 (0.44) | MEN1KMT2AF10 | |
| SCHEMBL7013030 | 0.75 | F10 (0.31) | F10 | |
| SCHEMBL6718580 | 0.70 | F10 (0.46) | F10NPSR1 | |
| SCHEMBL6714046 | 0.68 | F10 (0.58) | F10 | |
| SCHEMBL957292 | 0.66 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2HTTNPSR1 | |
| SCHEMBL5536664 | 0.65 | F10 (0.40) | MEN1KMT2AF10SMN1; SMN2TP53 | |
| SCHEMBL22581684 | 0.64 | MEN1 (0.59) | MEN1KMT2AADKCKS1BSKP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040077690-A1 | Quaternary amidino based inhibitors of factor xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-04-22 | — | — | US | disclosed |
| EP-1322637-A2 | QUATERNARY AMIDINO BASED INHIBITORS OF FACTOR XA | Millennium Pharmaceuticals, Inc. (US) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002026731-A2 | QUATERNARY AMIDINO BASED INHIBITORS OF FACTOR XA | MILLENIUM PHARMACEUTICALS, INC. (US) | 2002-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077690-A1 | Quaternary amidino based inhibitors of factor xa | F12, TFPI, F11 | MEN1 589/4885KMT2A 3079/4885F10 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.