Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 15/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 14/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9945767 | 0.79 | HSD11B1 (0.33) | — | |
| SCHEMBL16711606 | 0.76 | — | — | |
| SCHEMBL16711601 | 0.75 | — | — | |
| SCHEMBL1697305 | 0.71 | — | — | |
| SCHEMBL18306964 | 0.70 | — | — | |
| SCHEMBL21334351 | 0.70 | — | — | |
| SCHEMBL11656923 | 0.67 | NR1I2 (0.32) | — | |
| SCHEMBL12203400 | 0.66 | — | — | |
| SCHEMBL16711559 | 0.65 | — | — | |
| SCHEMBL17893058 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040030131-A1 | Pharmaceutical compounds | ELI LILLY AND COMPANY | 2004-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040030131-A1 | Pharmaceutical compounds | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, PYM1, CHRM1 | SLC6A3 621/4885SLC6A4 400/4885SLC6A2 1010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.