Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.55 |
| ▸ | CNR2 | P34972 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | THRA | P10827 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12460239 | 0.93 | CNR1 (0.52) | CNR1CNR2MEN1KMT2AHTT | |
| SCHEMBL30630917 | 0.91 | CNR1 (0.61) | CNR1CNR2MEN1KMT2AHTT | |
| SCHEMBL29802558 | 0.91 | CNR1 (0.61) | CNR1CNR2MEN1KMT2AHTT | |
| SCHEMBL29802338 | 0.91 | CNR1 (0.61) | CNR1CNR2MEN1KMT2AHTT | |
| SCHEMBL23271675 | 0.91 | CNR1 (0.61) | CNR1CNR2MEN1KMT2AHTT | |
| SCHEMBL23271677 | 0.91 | CNR1 (0.61) | CNR1CNR2MEN1KMT2AHTT | |
| SCHEMBL19612290 | 0.91 | CNR1 (0.61) | CNR1CNR2MEN1KMT2AHTT | |
| SCHEMBL29802382 | 0.91 | CNR1 (0.61) | CNR1CNR2MEN1KMT2AHTT | |
| SCHEMBL29802552 | 0.89 | CNR1 (0.60) | CNR1CNR2MEN1KMT2AHTT | |
| SCHEMBL25638485 | 0.87 | CNR1 (0.51) | CNR1CNR2MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470102-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | Applied Research Systems ARS Holding N.V. (AN) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003064376-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-08-07 | — | — | WO | disclosed |