Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 12/20 | 0.38 |
| ▸ | PGR | P06401 | 3/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6718231 | 0.86 | BRAF (0.40) | KITPGRBRD4PIK3CDEGFR | |
| SCHEMBL6718560 | 0.86 | PGR (0.40) | KITPGRBRD4SLC22A12 | |
| SCHEMBL6719197 | 0.85 | PGR (0.39) | KITPGRBRD4SLC22A12BRAF | |
| SCHEMBL6720421 | 0.85 | PGR (0.39) | KITPGRBRD4SLC22A12 | |
| SCHEMBL6719080 | 0.83 | PGR (0.38) | KITPGRBRD4SLC22A12 | |
| SCHEMBL6716009 | 0.83 | PGR (0.38) | KITPGRBRD4PIK3CDEGFR | |
| SCHEMBL6718645 | 0.82 | PGR (0.37) | KITPGRBRD4SLC22A12BRAF | |
| SCHEMBL6722813 | 0.82 | PGR (0.37) | KITPGRBRD4SLC22A12 | |
| SCHEMBL6831039 | 0.82 | PGR (0.37) | KITPGRBRD4SLC22A12 | |
| SCHEMBL6719193 | 0.79 | PGR (0.38) | KITPGRBRD4PIK3CDEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092402-A1 | Pyrimidine derivatives and herbicides containing the same | SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) | 2004-05-13 | — | — | US | disclosed |
| EP-1333029-A1 | PYRIMIDINE DERIVATIVES AND HERBICIDES CONTAINING THE SAME | Sumitomo Chemical Takeda Agro Company, Limited (JP) | 2003-08-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092402-A1 | Pyrimidine derivatives and herbicides containing the same | DDX41, CBR3, DPYD | KIT 3365/4885PGR 3190/4885BRD4 255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.