Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17949595 | 0.92 | BRD4 (0.44) | METAP2BRD4KDM4EHTTTSHR | |
| SCHEMBL16785780 | 0.91 | KDM4E (0.43) | METAP2BRD4KDM4EHTTTSHR | |
| SCHEMBL20249857 | 0.88 | METAP2 (0.39) | METAP2BRD4HTTTSHRMMP9 | |
| SCHEMBL19618539 | 0.85 | BRD4 (0.39) | METAP2BRD4KDM4EMMP9ATM | |
| SCHEMBL19618536 | 0.84 | TOP1 (0.40) | METAP2KDM4EMMP9LMNAMAPT | |
| SCHEMBL16561019 | 0.84 | FABP1 (0.42) | METAP2PDE4AFABP1 | |
| SCHEMBL20412448 | 0.84 | KDM4E (0.41) | METAP2KDM4EHTTTSHRTP53 | |
| SCHEMBL17899355 | 0.84 | CCR1 (0.41) | KDM4EHTTTSHRMMP9GMNN | |
| SCHEMBL16629751 | 0.84 | HTT (0.35) | METAP2KDM4EHTTTSHRMMP9 | |
| SCHEMBL16629631 | 0.83 | KDM4E (0.38) | METAP2BRD4KDM4EHTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040247933-A1 | Bipolar asymmetric carbazole-based host materials for electrophosphorescent guest-host OLED systems | CANON KABUSHIKI KAISHA (JP) | 2004-12-09 | — | — | US | disclosed |