Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9242015 | 0.98 | TSHR (0.42) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL22245749 | 0.92 | TSHR (0.41) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL4847032 | 0.89 | TSHR (0.47) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL28954002 | 0.88 | TSHR (0.41) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL24899647 | 0.88 | THRB (0.37) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL24899844 | 0.88 | THRB (0.37) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL7867278 | 0.87 | TSHR (0.42) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL24897227 | 0.86 | TSHR (0.31) | TSHRALDH1A1 | |
| SCHEMBL24897515 | 0.86 | TSHR (0.41) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL22245968 | 0.84 | TSHR (0.40) | TSHRALDH1A1TP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194511-B1 | COMPRISING POLYMERIZABLE MONOMER CONTAINING SULFUR-CONTAINING (METH)ACRYLATE POLYMERIZABLE MONOMER AND PHOTOCHROMIC COMPOUND | TOKUYAMA CORPORATION (JP) | 2001-02-27 | — | — | US | claimed |
| US-5776376-A | BLEND OF EPOXY AND UNSATURATED ESTER MONOMERS | TOKUYAMA CORPORATION (JP) | 1998-07-07 | — | — | US | claimed |
| EP-0559439-B1 | Photochromic composition | TOKUYAMA CORP (JP) | 1997-06-04 | — | — | EP | claimed |
| US-5395566-A | Addition polymerizable composition, epoxy monomer, imide or anhydride containing fused ring photochromic compound, lenses | TOKUYAMA CORPORATION (JP) | 1995-03-07 | — | — | US | claimed |
| EP-0619358-A1 | Photochromic composition | TOKUYAMA CORPORATION (JP) | 1994-10-12 | — | — | EP | claimed |
| EP-0559439-A2 | Photochromic composition | TOKUYAMA CORPORATION (JP) | 1993-09-08 | — | — | EP | claimed |
| EP-4692072-A1 | PHOTOCHROMIC COMPOUND, PROPARGYL ALCOHOL COMPOUND, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND SPECTACLES | TOKUYAMA CORPORATION (JP) | 2026-02-11 | — | — | EP | disclosed |
| US-20250355282-A1 | LAYERED BODY, OPTICAL ARTICLE, LENS, AND SPECTACLES | TOKUYAMA CORPORATION (JP) | 2025-11-20 | — | — | US | disclosed |
| US-12434265-B2 | Coating method | TOKUYAMA CORPORATION (JP) | 2025-10-07 | — | — | US | disclosed |
| EP-4560367-A1 | LAYERED BODY, OPTICAL ARTICLE, LENS, AND SPECTACLES | TOKUYAMA CORPORATION (JP) | 2025-05-28 | — | — | EP | disclosed |
| CN-114402008-B | Photochromic hydroxy carbamate compound | 株式会社德山 | 2024-07-19 | — | — | CN | disclosed |
| CN-115702176-B | Curable composition and cured product thereof | 株式会社德山 | 2024-05-03 | — | — | CN | disclosed |
| WO-2024018902-A1 | LAYERED BODY, OPTICAL ARTICLE, LENS, AND SPECTACLES | 株式会社トクヤマ | 2024-01-25 | — | — | WO | disclosed |
| US-5776376-A | BLEND OF EPOXY AND UNSATURATED ESTER MONOMERS | TOKUYAMA CORPORATION (JP) | 1998-07-07 | — | — | US | disclosed |
| US-5708063-A | REVERSABLE COLOR COMPOUNDS | TOKUYAMA CORPORATION (JP) | 1998-01-13 | — | — | US | disclosed |
| US-5631382-A | PHOTOCHROMIC LENSES | TOKUYAMA CORPORATION (JP) | 1997-05-20 | — | — | US | disclosed |
| EP-0773272-A1 | PHOTOCHROMIC CURABLE COMPOSITION | TOKUYAMA CORPORATION (JP) | 1997-05-14 | — | — | EP | disclosed |
| EP-0773273-A1 | PROCESS FOR THE PRODUCTION OF PHOTOCHROMIC PRODUCT OF CURING | TOKUYAMA CORPORATION (JP) | 1997-05-14 | — | — | EP | disclosed |
| EP-0696582-A1 | Polycyclic spirophthalimide derivatives, process for their preparation and their use as fulgimides | TOKUYAMA CORPORATION (JP) | 1996-02-14 | — | — | EP | disclosed |
| EP-0629626-A2 | Cyclopropyl-substituted spiro-photochromic compounds | TOKUYAMA CORPORATION (JP) | 1994-12-21 | — | — | EP | disclosed |