SCHEMBL6716660

SCHEMBL6716660

c1ccc(-c2c[nH]c([C@H]3Cc4c([nH]c5ccccc45)C4(CCCCCC4)N3)n2)cc1

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SSTR3 P32745 16/20 0.52
SSTR1 P30872 2/20 0.46
LMNA P02545 1/20 0.43
KCNH2 Q12809 4/20 0.42
SSTR4 P31391 2/20 0.42
SSTR5 P35346 2/20 0.42
CACNA1F O60840 2/20 0.42
CACNA1D Q01668 2/20 0.42
CACNA1S Q13698 2/20 0.42
CACNA1C Q13936 2/20 0.42
OPRM1 P35372 3/20 0.41
OGFRL1 Q5TC84 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6723618 0.91 SSTR3 (0.51) SSTR3SSTR1KCNH2SSTR4SSTR5
Hydrochloric Acid SCHEMBL6715693 0.83 SSTR3 (0.58) SSTR3SSTR1KCNH2SSTR4SSTR5
SCHEMBL7125957 0.81 SSTR3 (0.58) SSTR3KCNH2CACNA1FCACNA1DCACNA1S
SCHEMBL1244095 0.78 SSTR3 (0.70) SSTR3SSTR1KCNH2SSTR4SSTR5
SCHEMBL12890523 0.78 SSTR3 (0.70) SSTR3SSTR1KCNH2SSTR4SSTR5
SCHEMBL12912368 0.78 SSTR3 (0.70) SSTR3SSTR1KCNH2SSTR4SSTR5
Fumaric Acid SCHEMBL6714201 0.73 SSTR3 (0.64) SSTR3SSTR1KCNH2SSTR4SSTR5
Fumaric Acid SCHEMBL6714206 0.73 SSTR3 (0.64) SSTR3SSTR1KCNH2SSTR4SSTR5
SCHEMBL1714366 0.72 SSTR3 (0.64) SSTR3SSTR1KCNH2SSTR4SSTR5
SCHEMBL1715602 0.72 SSTR3 (0.64) SSTR3SSTR1KCNH2SSTR4SSTR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040038970-A1 Beta-carboline compounds SOCIETE DE CONSEILS DE RECHERCHES ETD' APPLICATION SCIENTIFIQUES, S.A.S. A PARIS, FRANCE CORP. 2004-02-26 US disclosed
US-6586445-B1 Racemic mixtures of 1,2,3,4-tetra hydro-1-(4-methoxyphenyl)-3 -(4-phenyl-1H-imidazol-2-yl)-9H- pyrido(3,4-b)indole, which bind to somatostatin receptors and block sodium channel modulators; antidiabetic, antiinflammatory agents; diarrhea Société de Conseils de Recherches et d'Applications Scientifiques, S.A.S. (FR) 2003-07-01 US disclosed
EP-1086101-B1 BETA-CARBOLINE COMPOUNDS SOD CONSEILS RECH APPLIC (FR) 2002-12-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040038970-A1 Beta-carboline compounds SCN1B, SCN2B, CACNA1B SSTR3 49/4885SSTR1 45/4885LMNA 2781/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.