Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.44 |
| ▸ | MAT2A | P31153 | 14/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL673296 | 0.80 | ENPP2 (0.56) | CYP1A2METAP2ENPP2MAT2APRMT5 | |
| SCHEMBL671669 | 0.78 | ENPP2 (0.48) | CYP1A2METAP2ENPP2MAT2APRMT5 | |
| SCHEMBL671137 | 0.76 | ENPP2 (0.48) | CYP1A2METAP2ENPP2MAT2APRMT5 | |
| SCHEMBL28062451 | 0.75 | ENPP2 (0.53) | CYP1A2METAP2ENPP2MAT2APRMT5 | |
| SCHEMBL670399 | 0.72 | ENPP2 (0.80) | CYP1A2METAP2ENPP2MAT2APRMT5 | |
| SCHEMBL19389470 | 0.72 | CYP1A2 (0.47) | CYP1A2METAP2ENPP2MAT2APRMT5 | |
| SCHEMBL670754 | 0.72 | ENPP2 (0.59) | CYP1A2METAP2ENPP2MAT2APRMT5 | |
| SCHEMBL672218 | 0.71 | ENPP2 (0.56) | CYP1A2METAP2ENPP2MAT2APRMT5 | |
| SCHEMBL670590 | 0.71 | ENPP2 (0.55) | CYP1A2METAP2ENPP2MAT2APRMT5 | |
| SCHEMBL671004 | 0.70 | ENPP2 (0.65) | CYP1A2METAP2ENPP2MAT2APRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2606031-A2 | AUTOTAXIN INHIBITORS AND USES THEREOF | Amira Pharmaceuticals, Inc. (US) | 2013-06-26 | — | — | EP | claimed |
| WO-2012024620-A2 | AUTOTAXIN INHIBITORS AND USES THEREOF | AMIRA PHARMACEUTICALS, INC. (US) | 2012-02-23 | — | — | WO | claimed |