SCHEMBL6716792

SCHEMBL6716792

Cc1cc(C)c(N(c2ccc(N(c3ccccc3)c3c(C)cc(C(C)(C)C)cc3C)cc2)c2ccc(N(c3ccccc3)c3c(C)cc(C(C)(C)C)cc3C)cc2)c(C)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.37
TACR1 P25103 1/20 0.35
CYP1A2 P05177 3/20 0.35
CYP3A4 P08684 2/20 0.35
CYP2C9 P11712 2/20 0.35
CYP2C19 P33261 2/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
POLB P06746 1/20 0.35
RXRB P28702 2/20 0.35
RXRA P19793 1/20 0.35
TSHR P16473 3/20 0.34
CRHR1 P34998 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
HTR1D P28221 2/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1087477 0.94 CYP2D6 (0.40) CYP2D6TACR1CYP1A2CYP3A4CYP2C9
SCHEMBL10354394 0.93 TSHR (0.43) CYP2D6TACR1CYP1A2CYP3A4CYP2C9
SCHEMBL13010224 0.93 TSHR (0.43) CYP2D6TACR1CYP1A2CYP3A4CYP2C9
SCHEMBL3768700 0.93 CYP2D6 (0.41) CYP2D6TACR1CYP1A2CYP3A4CYP2C9
SCHEMBL23894648 0.91 CYP2D6 (0.41) CYP2D6CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL13133421 0.91 CYP2D6 (0.41) CYP2D6CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL15854842 0.89 RXRB (0.39) CYP2D6CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL1086531 0.89 RXRB (0.39) CYP2D6CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL15854827 0.89 RXRB (0.39) CYP2D6CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL19901698 0.89 TSHR (0.46) KDM4EALDH1A1MAPTTDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120293749-A1 POLYMER COMPOUND AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-11-22 US disclosed
US-20120293749-A1 POLYMER COMPOUND AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-11-22 US disclosed
US-8263735-B2 Polymer compound and polymer light-emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-09-11 US disclosed
US-8263735-B2 Polymer compound and polymer light-emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-09-11 US disclosed
EP-1394188-B1 Polymer compound and polymer light-emitting device using the same SUMITOMO CHEMICAL CO (JP) 2011-02-02 EP disclosed
US-7772360-B2 Polymer compound and polymer light-emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-08-10 US disclosed
US-7772360-B2 Polymer compound and polymer light-emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-08-10 US disclosed
US-20100133997-A1 POLYMER COMPOUND AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-03 US disclosed
US-20100133997-A1 POLYMER COMPOUND AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-03 US disclosed
US-20040109955-A1 Polymer compound and polymer light-emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED 2004-06-10 US disclosed