Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HTR1D | P28221 | 2/20 | 0.33 |
| ▸ | RXRB | P28702 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12018768 | 0.96 | TSHR (0.50) | TSHRPOLBALDH1A1HCRTR2RAB9A | |
| SCHEMBL2607267 | 0.96 | TSHR (0.50) | TSHRPOLBALDH1A1HCRTR2RAB9A | |
| SCHEMBL14981042 | 0.92 | TSHR (0.58) | TSHRPOLBALDH1A1HCRTR2RAB9A | |
| SCHEMBL12018769 | 0.91 | TSHR (0.45) | TSHRPOLBALDH1A1HCRTR2RAB9A | |
| SCHEMBL15854846 | 0.91 | TSHR (0.45) | TSHRPOLBALDH1A1HCRTR2RAB9A | |
| SCHEMBL16615379 | 0.90 | TSHR (0.48) | TSHRPOLBALDH1A1HCRTR2RAB9A | |
| SCHEMBL13010224 | 0.89 | TSHR (0.43) | TSHRPOLBALDH1A1HCRTR2RAB9A | |
| SCHEMBL10354394 | 0.89 | TSHR (0.43) | TSHRPOLBALDH1A1HCRTR2RAB9A | |
| SCHEMBL6716792 | 0.89 | CYP2D6 (0.37) | TSHRPOLBALDH1A1RAB9AHTR1D | |
| SCHEMBL12018763 | 0.88 | ALDH1A1 (0.46) | TSHRALDH1A1RAPGEF4MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9905767-B2 | High-molecular compound and light-emitting element using same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-02-27 | — | — | US | disclosed |