SCHEMBL671705

SCHEMBL671705

O[C@@H](CBr)CCBr

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL620091 1.00
SCHEMBL422142 1.00
SCHEMBL7138282 0.85
SCHEMBL9535580 0.80
SCHEMBL39040 0.76
SCHEMBL1079184 0.76
SCHEMBL31672195 0.76
SCHEMBL4917221 0.76
SCHEMBL4925413 0.76
SCHEMBL947029 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2605772-B1 PROCESS FOR PREPARING AMINOCYCLOHEXYL ETHER COMPOUNDS CARDIOME INTERNAT AG (CH) 2016-06-22 EP claimed
US-20150259284-A1 PROCESS FOR PREPARING AMINOCYCLOHEXYL ETHER COMPOUNDS CARDIOME INTERNATIONAL SA (CH) 2015-09-17 US claimed
US-9006460-B2 Process for preparing aminocyclohexyl ether compounds CARDIOME INTERNATIONAL AG (CH) 2015-04-14 US claimed
EP-2605772-A2 PROCESS FOR PREPARING AMINOCYCLOHEXYL ETHER COMPOUNDS Merck Sharp & Dohme Corp. (US) 2013-06-26 EP claimed
US-20130149751-A1 PROCESS FOR PREPARING AMINOCYCLOHEXYL ETHER COMPOUNDS CARDIOME INTERNATIONAL SA (CH) 2013-06-13 US claimed
WO-2012024100-A2 PROCESS FOR PREPARING AMINOCYCLOHEXYL ETHER COMPOUNDS MERCK SHARP & DOHME CORP. (US) 2012-02-23 WO claimed
US-10106535-B2 Histone deacetylase inhibitors and compositions and methods of use thereof CHDI FOUNDATION, INC. (US) 2018-10-23 US disclosed
US-20170305900-A1 HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF CHDI FOUNDATION, INC. 2017-10-26 US disclosed
US-20170305900-A1 HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF CHDI FOUNDATION, INC. 2017-10-26 US disclosed
US-20170305900-A1 HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF CHDI FOUNDATION, INC. 2017-10-26 US disclosed
US-9783488-B2 Histone deacetylase inhibitors and compositions and methods of use thereof CHDI FOUNDATION, INC. (US) 2017-10-10 US disclosed
US-9783488-B2 Histone deacetylase inhibitors and compositions and methods of use thereof CHDI FOUNDATION, INC. (US) 2017-10-10 US disclosed
US-9783488-B2 Histone deacetylase inhibitors and compositions and methods of use thereof CHDI FOUNDATION, INC. (US) 2017-10-10 US disclosed
US-7390825-B1 Process for the preparation of oxazolidinones and method of use thereof BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2008-06-24 US disclosed
US-20080146458-A1 PROCESS FOR THE PREPARATION OF OXAZOLIDINONES AND METHOD OF USE THEREOF BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2008-06-19 US disclosed
US-20070265451-A1 Process for the preparation of oxazolidinones and method of use thereof BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2007-11-15 US disclosed
EP-1578723-A4 PROCESS FOR THE PREPARATION OF OXAZOLIDINONES AND METHOD OF USE THEREOF UNIV MICHIGAN STATE (US) 2006-11-02 EP disclosed
EP-1578723-A3 PROCESS FOR THE PREPARATION OF OXAZOLIDINONES AND METHOD OF USE THEREOF MICHIGAN STATE UNIVERSITY (US) 2005-10-20 EP disclosed
EP-1578723-A2 PROCESS FOR THE PREPARATION OF OXAZOLIDINONES AND METHOD OF USE THEREOF MICHIGAN STATE UNIVERSITY (US) 2005-09-28 EP disclosed
WO-2003106413-A2 PROCESS FOR THE PREPARATION OF OXAZOLIDINONES AND METHOD OF USE THEREOF MICHIGAN STATE UNIVERSITY (US) 2003-12-24 WO disclosed