⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11269206 | 0.81 | — | — | |
| SCHEMBL422142 | 0.80 | — | — | |
| SCHEMBL671705 | 0.80 | — | — | |
| SCHEMBL620091 | 0.80 | — | — | |
| SCHEMBL1141974 | 0.79 | — | — | |
| SCHEMBL3417763 | 0.79 | — | — | |
| SCHEMBL764404 | 0.77 | — | — | |
| SCHEMBL28823841 | 0.77 | — | — | |
| SCHEMBL7216727 | 0.77 | — | — | |
| SCHEMBL28581845 | 0.75 | FFAR4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2264735-A | — | — | None | — | — | JP | disclosed |
| EP-0304961-B1 | NOVEL DIPHOSPHONATES AND USE THEREOF IN PHARMACEUTICAL COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1993-08-11 | — | — | EP | disclosed |
| US-5104863-A | Certain bicycloalkane and azabicycloalkane-1,1-diphosphonic acid derivatives useful for treating diseases associated with abnormal calcium and phosphate metabolism | THE PROCTER & GAMBLE COMPANY (US) | 1992-04-14 | — | — | US | disclosed |
| JP-H02264735-A | BROMINATION OF TRIALCOHOL | NIPPON SYNTHETIC CHEM IND CO LTD:THE | 1990-10-29 | — | — | JP | disclosed |
| US-4939131-A | Certain cycloalkane-1,1-diphosphonic acids and derivatives thereof having the ability to treat diseases associated with abnormal calcium and phosphate metabolism | THE PROCTER & GAMBLE COMPANY (US) | 1990-07-03 | — | — | US | disclosed |
| EP-0304962-A2 | Novel diphosphonates and use thereof in pharmaceutical compositions | THE PROCTER & GAMBLE COMPANY (US) | 1989-03-01 | — | — | EP | disclosed |
| EP-0304961-A2 | Novel diphosphonates and use thereof in pharmaceutical compositions | THE PROCTER & GAMBLE COMPANY (US) | 1989-03-01 | — | — | EP | disclosed |
| US-4687768-A | OSTEOPOROSIS, ARTHRITIS | THE PROCTER & GAMBLE COMPANY (US) | 1987-08-18 | — | — | US | disclosed |
| EP-0189662-A1 | Novel diphosphonates and use thereof in pharmaceutical compositions | THE PROCTER & GAMBLE COMPANY (US) | 1986-08-06 | — | — | EP | disclosed |