Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | PYGB | P11216 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28155328 | 0.92 | MAPK1 (0.41) | MAPK1ADORA2AADORA2BGBA1PYGB | |
| SCHEMBL27530777 | 0.87 | MAPK1 (0.36) | MAPK1ADORA2AADORA2BGBA1PYGB | |
| SCHEMBL5149118 | 0.82 | MAPK1 (0.39) | MAPK1ADORA2AADORA2BGBA1PYGB | |
| SCHEMBL671123 | 0.80 | TSHR (0.42) | MAPK1PYGB | |
| SCHEMBL8401721 | 0.80 | PRKCA (0.42) | MAPK1 | |
| SCHEMBL4953623 | 0.79 | MAPK1 (0.39) | MAPK1ADORA2AADORA2BGBA1PYGB | |
| SCHEMBL14975911 | 0.78 | MAPK1 (0.37) | MAPK1MEN1THRBHTTKMT2A | |
| SCHEMBL8864783 | 0.78 | MAPK1 (0.38) | MAPK1ADORA2AADORA2BGBA1PYGB | |
| SCHEMBL8864165 | 0.78 | MAPK1 (0.38) | MAPK1ADORA2AADORA2BGBA1PYGB | |
| SCHEMBL7804811 | 0.78 | MAPK1 (0.38) | MAPK1ADORA2AADORA2BGBA1PYGB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012024688-A1 | MULTIPHASE SYSTEMS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-02-23 | — | — | WO | disclosed |