Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 9/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544356 | 0.84 | HPGD (0.56) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL27860093 | 0.84 | PDE4D (0.56) | PDE4DMAPTTDP1MEN1KMT2A | |
| SCHEMBL6717832 | 0.84 | PDE4D (0.56) | PDE4DMAPTTDP1MEN1KMT2A | |
| SCHEMBL4255074 | 0.83 | PDE4D (0.53) | PDE4DMAPTTDP1MEN1KMT2A | |
| SCHEMBL11678563 | 0.82 | PDE4D (0.55) | PDE4DMAPTTDP1MEN1KMT2A | |
| SCHEMBL4608592 | 0.82 | PDE4D (0.55) | PDE4DMAPTTDP1MEN1KMT2A | |
| SCHEMBL4312690 | 0.82 | HPGDS (0.61) | PDE4DMAPTTDP1MEN1KMT2A | |
| SCHEMBL222062 | 0.79 | MAPT (0.55) | PDE4DMAPTTDP1MEN1KMT2A | |
| SCHEMBL11680967 | 0.79 | PDE4D (0.52) | PDE4DMAPTTDP1MEN1KMT2A | |
| SCHEMBL4118586 | 0.79 | HTT (0.53) | PDE4DMAPTTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |