Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17220439 | 0.86 | THRB (0.50) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL3561624 | 0.85 | ELANE (0.50) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL10885204 | 0.85 | POLB (0.48) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL29315871 | 0.83 | CA1 (0.49) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL20364324 | 0.83 | POLB (0.49) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL25237883 | 0.82 | POLB (0.52) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL14944759 | 0.81 | POLB (0.54) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL5435399 | 0.80 | THRB (0.65) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL12404362 | 0.80 | THRB (0.49) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL6290863 | 0.80 | POLB (0.44) | THRBTSHRPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2596082-B1 | POLYMER-STABILIZED LIQUID-CRYSTAL MEDIA AND DISPLAYS | MERCK PATENT GMBH (DE) | 2015-11-04 | — | — | EP | disclosed |
| EP-2596082-A1 | POLYMER-STABILIZED LIQUID-CRYSTAL MEDIA AND DISPLAYS | Merck Patent GmbH (DE) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012022388-A1 | POLYMER-STABILIZED LIQUID-CRYSTAL MEDIA AND DISPLAYS | MERCK PATENT GMBH (DE) | 2012-02-23 | — | — | WO | disclosed |