Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.35 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6181311 | 0.98 | KDM4E (0.41) | KDM4ELMNABLMNPSR1CYP3A4 | |
| SCHEMBL1902161 | 0.98 | KDM4E (0.41) | KDM4ELMNABLMNPSR1CYP3A4 | |
| SCHEMBL9032838 | 0.79 | KMT2A (0.47) | KDM4EALDH1A1MAP3K7TAB1GAA | |
| SCHEMBL7318845 | 0.79 | MAP3K7 (0.39) | MAP3K7TAB1 | |
| SCHEMBL10540316 | 0.79 | MAP3K7 (0.39) | MAP3K7TAB1 | |
| SCHEMBL9326981 | 0.78 | KDM4E (0.46) | KDM4ELMNABLMNPSR1CYP3A4 | |
| SCHEMBL6181182 | 0.77 | CA12 (0.46) | KDM4ECYP3A4ALDH1A1GAAHCAR2 | |
| SCHEMBL6726458 | 0.77 | CA12 (0.46) | KDM4ECYP3A4ALDH1A1GAAHCAR2 | |
| SCHEMBL9129568 | 0.76 | KDM4E (0.41) | KDM4ELMNABLMNPSR1CYP3A4 | |
| SCHEMBL31324241 | 0.76 | KDM4E (0.41) | KDM4ELMNABLMNPSR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1439885-A1 | SIMPLIFIED SARCODICTYN DERIVATIVES AS ANTI-TUMOR AGENTS | Pharmacia Italia S.p.A. (IT) | 2004-07-28 | — | — | EP | disclosed |
| WO-2003024529-A1 | SIMPLIFIED SARCODICTYN DERIVATIVES AS ANTI-TUMOR AGENTS | PHARMACIA ITALIA SPA (IT) | 2003-03-27 | — | — | WO | disclosed |