⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31462905 | 1.00 | — | — | |
| SCHEMBL29176442 | 0.92 | — | — | |
| SCHEMBL6718492 | 0.78 | GABRA1 (0.31) | — | |
| SCHEMBL6719860 | 0.77 | PDE4A (0.31) | — | |
| SCHEMBL2115437 | 0.75 | — | — | |
| SCHEMBL15685059 | 0.74 | — | — | |
| SCHEMBL6722899 | 0.74 | — | — | |
| SCHEMBL31462876 | 0.74 | RPS6KB1 (0.30) | — | |
| SCHEMBL19743731 | 0.74 | — | — | |
| SCHEMBL31351992 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119751423-A | Pyrimidine-containing aryl pyrazole oxime ether compound as well as preparation method and application thereof | 河南大学 | 2025-04-04 | — | — | CN | disclosed |
| CN-118206527-A | N-pyridine ethyl pyrimidine amine compound | 湖南化工研究院有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-114516841-B | N-aryloxy/thiobenzyl difluoromethyl pyrilamine compound, and preparation method and application thereof | 湖南海利常德农药化工有限公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-114516868-B | N-heteroaryl methyl difluoromethyl pyrimidine amine compound, and preparation method and application thereof | 湖南海利常德农药化工有限公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-116655541-A | Fluorine-containing pyrimidine amine compound and application thereof | 青岛科技大学 | 2023-08-29 | — | — | CN | disclosed |
| EP-3760617-B1 | SUBSTITUTED PYRIMIDINE COMPOUND AND USES THEREOF | SHENYANG SINOCHEM AGROCHEMICALS R & D CO LTD (CN) | 2023-03-22 | — | — | EP | disclosed |
| CN-113754637-B | Pyridine ether compound containing pyrimidinamine | 湖南化工研究院有限公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-114516841-A | N-aryloxy/sulfur benzyl difluoromethyl pyrimidinamine compound and preparation method and application thereof | 湖南海利常德农药化工有限公司 | 2022-05-20 | — | — | CN | disclosed |
| CN-114516868-A | N-heteroaryl methyl difluoromethyl pyrimidinamine compound and preparation method and application thereof | 湖南海利常德农药化工有限公司 | 2022-05-20 | — | — | CN | disclosed |
| CN-113754637-A | Pyridine ether compound containing pyrimidinamine | 湖南化工研究院有限公司 | 2021-12-07 | — | — | CN | disclosed |
| US-20150257385-A1 | Substituted Pyrimidine Compound and Uses Thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2015-09-17 | — | — | US | disclosed |
| EP-2913325-A1 | SUBSTITUTED PYRIMIDINE COMPOUND AND USES THEREOF | Sinochem Corporation (CN) | 2015-09-02 | — | — | EP | disclosed |
| EP-2913325-A1 | SUBSTITUTED PYRIMIDINE COMPOUND AND USES THEREOF | Sinochem Corporation (CN) | 2015-09-02 | — | — | EP | disclosed |
| US-20150225378-A1 | HOMOPIPERONY LAMINE COMPOUND AND USE THEREOF | SINOCHEM CORPORATION (CN) | 2015-08-13 | — | — | US | disclosed |
| US-20150225378-A1 | HOMOPIPERONY LAMINE COMPOUND AND USE THEREOF | SINOCHEM CORPORATION (CN) | 2015-08-13 | — | — | US | disclosed |
| US-20150225378-A1 | HOMOPIPERONY LAMINE COMPOUND AND USE THEREOF | SINOCHEM CORPORATION (CN) | 2015-08-13 | — | — | US | disclosed |
| WO-2014063642-A1 | SUBSTITUTED PYRIMIDINE COMPOUND AND USES THEREOF | 中国中化股份有限公司 (CN) | 2014-05-01 | — | — | WO | disclosed |
| US-20040092402-A1 | Pyrimidine derivatives and herbicides containing the same | SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) | 2004-05-13 | — | — | US | disclosed |
| CN-1473155-A | Pyrimidine derivatives and herbicides containing the same | ס������ũҩ��ʽ���� | 2004-02-04 | — | — | CN | disclosed |
| EP-1333029-A1 | PYRIMIDINE DERIVATIVES AND HERBICIDES CONTAINING THE SAME | Sumitomo Chemical Takeda Agro Company, Limited (JP) | 2003-08-06 | — | — | EP | disclosed |