⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1625393 | 0.67 | — | — | |
| SCHEMBL4452756 | 0.63 | — | — | |
| SCHEMBL403109 | 0.63 | — | — | |
| SCHEMBL3293710 | 0.61 | — | — | |
| SCHEMBL3068150 | 0.61 | SCN4A (0.62) | — | |
| SCHEMBL4713585 | 0.61 | — | — | |
| SCHEMBL1930967 | 0.58 | — | — | |
| SCHEMBL155499 | 0.57 | — | — | |
| SCHEMBL18404 | 0.57 | — | — | |
| SCHEMBL157023 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3774744-B1 | COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | PTC THERAPEUTICS INC (US) | 2025-02-12 | — | — | EP | claimed |
| EP-3997096-B1 | NEW HETEROCYCLIC COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2024-08-28 | — | — | EP | claimed |
| US-20230183237-A1 | COMPETITIVE AND NONCOMPETITIVE INHIBITORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M5 | VANDERBILT UNIVERSITY | 2023-06-15 | — | — | US | claimed |
| CN-115572281-B | Synthetic method of 3-bromo-1- (3-chloro-2-pyridyl) -1H-pyrazole-5-formic acid | 苏州开元民生科技股份有限公司 | 2023-03-10 | — | — | CN | claimed |
| CN-108017651-B | The method of 1 inhibitor of synthetic cell cycle detection point kinases | 天津师范大学 | 2019-11-26 | — | — | CN | claimed |
| CN-108473495-A | Purinones as ubiquitin-specific protease 1 inhibitors | 福马治疗有限公司 | 2018-08-31 | — | — | CN | claimed |
| CN-108017651-A | The method of 1 inhibitor of synthetic cell cycle detection point kinases | 天津师范大学 | 2018-05-11 | — | — | CN | claimed |
| CN-104271132-B | Anticancer compounds targeting Ral gtpase and methods of using the same | 科罗拉多大学董事会法人团体 | 2018-01-12 | — | — | CN | claimed |
| CN-105189464-B | Cyclopenta pyrazoles as N-type calcium channel blocker | 詹森药业有限公司 | 2017-12-12 | — | — | CN | claimed |
| CN-106604731-A | Anticancer compounds targeting RAL GTPase and methods of using the same | 科罗拉多大学董事会法人团体 | 2017-04-26 | — | — | CN | claimed |
| EP-3057430-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | Dow AgroSciences LLC (US) | 2016-08-24 | — | — | EP | claimed |
| CN-105189464-A | Cyclopentylpyrazoles as N-type calcium channel blockers | JANSSEN PHARMACEUTICA NV | 2015-12-23 | — | — | CN | claimed |
| WO-2015058028-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2015-04-23 | — | — | WO | claimed |
| CN-104271132-A | Anticancer compounds targeting Ral gtpase and methods of using the same | UNIV COLORADO | 2015-01-07 | — | — | CN | claimed |
| EP-2643310-A1 | 4- (5-CYANO-PYRAZOL-1-YL) -PIPERIDINE DERIVATIVES AS GPR 119 MODULATORS | Pfizer Inc (US) | 2013-10-02 | — | — | EP | claimed |
| WO-2012069948-A1 | 4- (5-CYANO-PYRAZOL-1-YL) -PIPERIDINE DERIVATIVES AS GPR 119 MODULATORS | PFIZER INC. (US) | 2012-05-31 | — | — | WO | claimed |
| JP-2002516909-A | — | — | 2002-06-11 | — | — | JP | claimed |
| WO-1999062885-A1 | SUBSTITUTED 1-(4-AMINOPHENYL)PYRAZOLES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1999-12-09 | — | — | WO | claimed |
| US-20260102404-A1 | THYROID STIMULATING HORMONE RECEPTOR (TSHR) ANTAGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2026-04-16 | — | — | US | disclosed |
| EP-0174798-A1 | Process for preparing a pyrazole herbicide | ELI LILLY AND COMPANY (US) | 1986-03-19 | — | — | EP | disclosed |