Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.47 |
| ▸ | PPARA | Q07869 | 5/20 | 0.47 |
| ▸ | PPARD | Q03181 | 3/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 5/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6023224 | 0.81 | CYSLTR2 (0.38) | PPARGPPARACNR2CYP2C9CYP1A2 | |
| SCHEMBL5047584 | 0.80 | MEN1 (0.42) | PPARGPPARAPPARDSLC2A1CNR1 | |
| SCHEMBL1856734 | 0.77 | PPARG (0.41) | PPARGPPARAPPARDSLC2A1CNR1 | |
| SCHEMBL4319082 | 0.74 | PPARG (0.43) | PPARGPPARAPPARDSLC2A1CNR1 | |
| SCHEMBL1852713 | 0.74 | ACACB (0.51) | FAAH | |
| SCHEMBL6721621 | 0.74 | CYP3A4 (0.40) | PPARGPPARACYP2C9CYP1A2CYP3A4 | |
| SCHEMBL4978882 | 0.74 | PLK1 (0.47) | PPARACYP2C9CYP1A2SMN1; SMN2FAAH | |
| SCHEMBL1853877 | 0.72 | SLC2A1 (0.55) | PPARGPPARAPPARDSLC2A1CNR1 | |
| SCHEMBL1855967 | 0.72 | SLC2A1 (0.43) | PPARGPPARAPPARDSLC2A1CNR1 | |
| SCHEMBL1852984 | 0.71 | MLYCD (0.51) | PPARGPPARAPPARDCYP2C9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470102-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | Applied Research Systems ARS Holding N.V. (AN) | 2004-10-27 | — | — | EP | claimed |
| WO-2003064376-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-08-07 | — | — | WO | claimed |