Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 7/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.45 |
| ▸ | PDE4A | P27815 | 3/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | AKT2 | P31751 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21682416 | 0.82 | ADORA2B (0.54) | ADORA2BADORA3ADORA2APDE4APDE4B | |
| SCHEMBL9244067 | 0.75 | ADORA2B (0.53) | ADORA2BADORA3ADORA2APDE4APDE4B | |
| SCHEMBL2520260 | 0.68 | ADORA2B (1.00) | ADORA2BADORA3ADORA2APDE4APDE4B | |
| SCHEMBL11390728 | 0.67 | ADORA2B (0.60) | ADORA2BADORA3ADORA2APDE4APDE4B | |
| SCHEMBL447390 | 0.66 | ADORA2B (0.64) | ADORA2BADORA3ADORA2APDE4APDE4B | |
| SCHEMBL7296248 | 0.65 | ADORA2A (0.61) | ADORA2BADORA3ADORA2APDE4APDE4B | |
| SCHEMBL7295708 | 0.65 | ADORA2A (0.61) | ADORA2BADORA3ADORA2APDE4APDE4B | |
| Hydrochloric Acid SCHEMBL7296127 | 0.65 | ADORA2B (0.62) | ADORA2BADORA3ADORA2APDE4APDE4B | |
| SCHEMBL7801074 | 0.64 | ADORA2B (0.56) | ADORA2BADORA3ADORA2APDE4APDE4B | |
| SCHEMBL6141778 | 0.64 | ADORA2A (0.64) | ADORA2BADORA3ADORA2APDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102596191-B | pharmaceutical composition comprising BI-1356 and metformin | 勃林格殷格翰国际有限公司 | 2016-12-21 | — | — | CN | claimed |
| US-20040097510-A1 | 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097510-A1 | 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions | DPP8, DPP4, DPP3 | ADORA2B 470/4885ADORA3 120/4885ADORA2A 497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.