Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.46 |
| ▸ | WNT3A | P56704 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | TPMT | P51580 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13545220 | 0.85 | MEN1 (0.59) | PDE4DTSHRCTNNB1WNT3AMAPT | |
| SCHEMBL8680313 | 0.84 | TSHR (0.63) | PDE4DTSHRCTNNB1WNT3AMAPT | |
| SCHEMBL23112630 | 0.83 | GSK3B (0.54) | PDE4DTSHRCTNNB1WNT3AMAPT | |
| SCHEMBL7482554 | 0.83 | PDE4B (0.42) | PDE4D | |
| SCHEMBL6361805 | 0.82 | PDE4D (0.49) | PDE4DTSHRCTNNB1WNT3AMAPT | |
| SCHEMBL16954378 | 0.81 | MAPT (0.43) | PDE4DTSHRMAPTLMNACYP1A2 | |
| SCHEMBL141068 | 0.81 | HTT (0.49) | TSHRCTNNB1WNT3AMAPTLMNA | |
| SCHEMBL27456578 | 0.80 | CYP1A2 (0.68) | TSHRMAPTLMNACYP1A2CYP3A4 | |
| SCHEMBL7432445 | 0.80 | MAPT (0.57) | PDE4DTSHRCTNNB1WNT3AMAPT | |
| SCHEMBL3856127 | 0.79 | CYP1A2 (0.50) | PDE4DTSHRMAPTLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101270117-B | Herbicide and preparation thereof | UNIV DALIAN TECH | 2012-02-29 | — | — | CN | claimed |
| CN-101279972-B | Benzoxazole herbicides and preparation thereof | UNIV DALIAN TECH | 2011-02-02 | — | — | CN | claimed |
| CN-101870677-A | 5-arylmethoxy phenyl pyrazole compound and preparation method thereof | UNIV DALIAN TECH | 2010-10-27 | — | — | CN | claimed |
| CN-101279972-A | Benzoxazole herbicides and preparation thereof | UNIV DALIAN TECH (CN) | 2008-10-08 | — | — | CN | claimed |
| CN-101270117-A | Herbicide and preparation thereof | UNIV DALIAN TECH (CN) | 2008-09-24 | — | — | CN | claimed |
| CN-101270117-B | Herbicide and preparation thereof | UNIV DALIAN TECH | 2012-02-29 | — | — | CN | disclosed |
| CN-101279972-B | Benzoxazole herbicides and preparation thereof | UNIV DALIAN TECH | 2011-02-02 | — | — | CN | disclosed |
| CN-101870677-A | 5-arylmethoxy phenyl pyrazole compound and preparation method thereof | UNIV DALIAN TECH | 2010-10-27 | — | — | CN | disclosed |
| CN-101279972-A | Benzoxazole herbicides and preparation thereof | UNIV DALIAN TECH (CN) | 2008-10-08 | — | — | CN | disclosed |
| CN-101270117-A | Herbicide and preparation thereof | UNIV DALIAN TECH (CN) | 2008-09-24 | — | — | CN | disclosed |
| EP-0791571-B1 | Benzoyl derivatives | BAYER CROPSCIENCE AG (DE) | 2004-06-16 | — | — | EP | disclosed |
| US-20040092402-A1 | Pyrimidine derivatives and herbicides containing the same | SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) | 2004-05-13 | — | — | US | disclosed |
| CN-1090845-A | Process for preparing substituted aryl-halogenoalkyl pyrazoles | MONSANTO CO (US) | 1994-08-17 | — | — | CN | disclosed |
| US-5281571-A | Herbicidal benzoxazinone- and benzothiazinone-substituted pyrazoles | MONSANTO COMPANY (US) | 1994-01-25 | — | — | US | disclosed |
| EP-0553307-A1 | HERBICIDAL SUBSTITUTED ARYL-HALOALKYLPYRAZOLES | MONSANTO COMPANY (US) | 1993-08-04 | — | — | EP | disclosed |
| EP-0542872-A1 | HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES | MONSANTO COMPANY (US) | 1993-05-26 | — | — | EP | disclosed |
| CN-1061777-A | Substituted aryl-haloalkyl-pyrazoles as herbicides | MONSANTO CO (US) | 1992-06-10 | — | — | CN | disclosed |
| CN-1061221-A | The aryl alkylsulfonyl pyrazoles of the replacement of weeding | MONSANTO CO (US) | 1992-05-20 | — | — | CN | disclosed |
| WO-1992006962-A1 | HERBICIDAL SUBSTITUTED ARYL-HALOALKYLPYRAZOLES | MONSANTO COMPANY (US) | 1992-04-30 | — | — | WO | disclosed |
| WO-1992002509-A1 | HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES | MONSANTO COMPANY (US) | 1992-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092402-A1 | Pyrimidine derivatives and herbicides containing the same | DDX41, CBR3, DPYD | PDE4D 3003/4885TSHR 2182/4885CTNNB1 1654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.